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      • Trusted Partner
        August 2024

        Antiparasitic Drug Resistance in Veterinary Practice

        by Hafiz Muhammad Rizwan, Muhammad Ahsan Naeem, Muhammad Younus, Muhammad Sohail Sajid, Xi Chen, Haider Abbas, Tooba Abbas, S.W. Abbasi, Z. Afsheen, A. Ahmad

        Lack of clean water, inadequate sanitation, and insufficient infection prevention and control promote the spread of parasites. The discovery of antiparasitic drugs was considered a milestone in the veterinary and medical sciences, but their use has subsequently become limited due to the emergence of resistance. While plenty of attention has been given in human and animal health communities to the global threat of antimicrobial drug resistance, specific antiparasitic advice is less available. This book provides an in-depth view of the issue for parasitologists, pharmacologists and veterinary scientists. Specifically discussing antiparasitic drug resistance mechanisms and factors responsible for the problem, it covers: The physiological basis of parasitism; Resistance across protozoa, helminths, insects, mites and ticks; Molecular and phenotypic diagnostic methods; Practical strategies for mitigating resistance development. While it is clear that the veterinary field urgently requires the development of new antiparasitic drugs, of equal or even increased importance is the evaluation of alternative therapies and formulation of stringent policies to ensure appropriate drug use in veterinary practice. Highlighting the importance and development of resistance across different parasite groups, this book covers factors responsible for resistance development and advises strategies for effective stewardship and resistance mitigation.

      • Trusted Partner
        2020

        Mutschler’s Drug Actions

        Pharmacology – Clinical Pharmacology – Toxicology

        by Prof. Dr. Dr. Gerd Geisslinger, Dr. Sabine Menzel, Prof. Dr. Thomas Gudermann, Prof. Dr. Burkhard Hinz and Prof. Dr. Peter Ruth. Founded by Prof. Dr. Dr. Dres. h.c. Ernst Mutschler

        For half a century, “Mutschler” has been the standard reference work on pharmacology and toxicology – always forward-looking and at the cutting edge. The 11th edition continues this approach: ■ Up-to-the-minute: new drugs, including biologicals, relevant guidelines in the context of evidence-based medicine ■ Clearly structured: completely new layout with the focus on indication-related pharmacotherapy; uniformly constructed concise chapters ■ Well-illustrated: with many figures and tables, completely revised ■ Easy to remember: readily understandable explanations – even of complex issues ■ Critical: objective, independent assessment of the clinical value of drugs and drug groups ■ Comprehensive: with short introductions into the principles of anatomy, physiology and pathophysiology in the individual chapters ■ Reliable: full coverage of the subjects usually tested in the medical and pharmaceutical state examinations   The proven source for complete knowledge about the actions of drugs: for students and practitioners.

      • Trusted Partner
        2022

        Drugs as Micronutrient Robbers

        What your doctor and pharmacist ought to tell you

        by Uwe Gröber and Prof. Dr. Klaus Kisters

        Many of us have to take drugs on a regular basis. But birth control pills, antibiotics, blood pressure medication, statins, diabetes medication, diuretics, anti-cancer drugs, gastrointestinal remedies or preparations against osteoporosis can all rob the body of essential vitamins and minerals. Often, drug-related micronutrient deficiency is the unrecognized cause of drug side effects. Symptoms such as exhaustion, depression, lack of concentration, irritability, sleep disorders or even dementia can result. Such problems can be prevented. Informed patients can take preventive measures, avoid unwanted side effects and make their drug therapy more effective. This guide explains what to watch out for and how to improve quality of life.

      • Trusted Partner
        Humanities & Social Sciences
        March 2019

        Managing diabetes, managing medicine

        Chronic disease and clinical bureaucracy in post-war Britain

        by Martin D. Moore, Keir Waddington, David Cantor

        This book is available as an open access ebook under a CC-BY-NC-ND licence. Through its study of diabetes care in twentieth-century Britain, Managing diabetes, managing medicine offers the first historical monograph to explore how the decision-making and labour of medical professionals became subject to bureaucratic regulation and managerial oversight. Where much existing literature has cast health care management as either a political imposition or an assertion of medical control, this work positions managerial medicine as a co-constructed venture. Although driven by different motives, doctors, nurses, professional bodies, government agencies and international organisations were all integral to the creation of managerial systems, working within a context of considerable professional, political, technological, economic and cultural change.

      • Trusted Partner
        Humanities & Social Sciences
        January 2022

        Exiting war

        The British Empire and the 1918–20 moment

        by Romain Fathi, Margaret Hutchison, Andrekos Varnava, Michael Walsh, Alan Lester

        Exiting war explores a particular 1918-20 'moment' in the British Empire's history, between the First World War's armistices of 1918, and the peace treaties of 1919 and 1920. That moment, we argue, was a challenging and transformative time for the Empire. While British authorities successfully answered some of the post-war tests they faced, such as demobilisation, repatriation, and fighting the widespread effects of the Spanish flu, the racial, social, political and economic hallmarks of their imperialism set the scene for a wide range of expressions of loyalties and disloyalties, and anticolonial movements. The book documents and conceptualises this 1918-20 'moment' and its characteristics as a crucial three-year period of transformation for and within the Empire, examining these years for the significant shifts in the imperial relationship that occurred and as laying the foundation for later change in the imperial system.

      • Trusted Partner
        2024

        Intoxicating Drugs

        Known and new psychoactive substances

        by Prof. Dr. Niels Eckstein

        Intoxicating? Intoxicating drugs are as old as mankind itself. Whether herbal or produced synthetically in a laboratory, their variety is almost limitless. And every year, more substances are added to the list. Niels Eckstein, who is a Professor of Drug Regulatory Affairs and Pharmacology and a long-standing expert in the narcotics scene, explores the abysses of the darknet and dealer hell, provides insider information, conducts interviews with dealers and producers, and offers profound insights into the bizarre, parallel world of intoxicating substances. At the same time, the author takes a thorough look at the chemistry of the different substance classes and the neurobiological basis of addiction. He also covers production and assesses the danger and addiction potential of designer drugs, BTM, NPS, medicinal drugs and doping substances. This book outlines the political and sociopolitical dimensions of the use of psychoactive substances, classifies them legally, describes risks, approaches, and help strategies, highlights routes out of drug problems and alternatives to drug prohibition, and comments on the opioid crisis in the United States and the „war on drugs.“ “I don‘t care how it‘s regulated: if he wants it and can pay for it, he gets it. If I get caught, I‘ll go to jail for a few years, whether it‘s for a kilo of coke, meph or testo, it doesn‘t matter.“ – In an interview with a dealer

      • Trusted Partner
        2023

        Medication Analysis

        Basic principles and case examples

        by Pharm. D. Ina Richling

        Several different pills prescribed by many different physicians: pharmacists encounter patients in this situation every day! What at first seems quite normal can, on closer inspection, be fraught with considerable risks of drug-related problems. Using this analysis as a core component of medication management, pharmacies have the key risk minimisation tool at their disposal. The authors guide their readers step by step through the discussions with the patient, the stages of the analysis, and the clear documentation. Case examples reflect on the content and illustrate implementation. The launch of pharmaceutical services enables an improvement in the safety and efficacy of customers‘ drug therapy in the pharmacy by means of the service „Extended medication counselling for polymedication“. Everything pharmacists need to know for the necessary medication analysis can be found in this book. This completely revised 2nd edition includes: - Important information on pharmaceutical services - Illustrative case examples on many indications - QR codes that lead to additional digital material Whether it is a detailed adjustment or a major change to medication: every patient benefits from the intervention.

      • Trusted Partner
        2021

        aporello - Drugs in Palliative Medicine

        by Christian Redmann

        In the last stage of life, it is all about giving care in a professional manner and providing efficient relief of suffering. In addition to all the important key points about in-label use, this book consisting of drug monographs, includes: - Information about off-label indications with dosages, - Lists of the different dosage forms available, - Instructions about use in renal failure. A clear structure and icons enable rapid orientation in everyday practice. Focussed knowledge at your fingertips? That’s aporello!

      • Trusted Partner
        2020

        Biogenic Drugs

        Textbook of pharmaceutical biology

        by Prof. Dr. Eberhard Teuscher, Prof. Dr. Ulrike Lindequist and Prof. Dr. Matthias F. Melzig. In collaboration with Dr. Elke Langner, Prof. Dr. Timo Niedermeyer and Dr. Alexander Wenig

        The new Teuscher covers the range of relevant areas of biogenic drug substances and medicinal products. In its time-honoured way, it conveys knowledge about the ■ Nature, origin and processing of crude drugs ■ Structure, biosynthesis and metabolism of the constituents ■ Preparation, pharmacology and use of the active substances ■ Dosage and side effects of the medicinal products derived from them The book deals with both classically produced and genetically engineered antibiotics, hormones, enzymes as well as blood and immunological products. Completely new chapters discuss cytokines, gene therapy, use of stem cells and traditional Chinese medicine. For generations, the textbook and companion for both students and fully qualified professionals!

      • Trusted Partner
        May 2022

        In the Shadow of War

        Diary notes from Ukraine

        by Christoph Brumme

        "What can you learn in war? Do you become numb, do you get used to it at some point? Does war make you "hard", uncaring, above pain? No. These are just clichés. Every day brings new horrors. At best, one learns for some time to suppress strong feelings, because to give in to them would weaken one's life instinct." In a very stirring and shocking, but sometimes humorous language, Christoph Brumme tells of the situation in Ukraine, the everyday life of his family and friends, of fears, longings and political assessments. The diary entries of the war and the resistance of the Ukrainians, starting from the first signs of the impending war in mid-January 2022 until the printing of this book, 1st May 2022, impressively bear witness to the brutality of these events.

      • Trusted Partner
        The Arts
        September 2024

        The renewal of post-war Manchester

        Planning, architecture and the state

        by Richard Brook

        A compelling account of the project to transform post-war Manchester, revealing the clash between utopian vision and compromised reality. Urban renewal in Britain was thrilling in its vision, yet partial and incomplete in its implementation. For the first time, this deep study of a renewal city reveals the complex networks of actors behind physical change and stagnation in post-war Britain. Using the nested scales of region, city and case-study sites, the book explores the relationships between Whitehall legislation, its interpretation by local government planning officers and the on-the-ground impact through urban architectural projects. Each chapter highlights the connections between policy goals, global narratives and the design and construction of cities. The Cold War, decolonialisation, rising consumerism and the oil crisis all feature in a richly illustrated account of architecture and planning in post-war Manchester.

      • Trusted Partner
        2022

        Drug knowledge

        Index cards for pharmacy-only andprescription-only active substances

        by Dr. Thomas Wurm

        With the huge number of medicinal products, it is easy to get lost in the pharmaceutical jungle. Clearly divided into over-the-counter medicines, prescription-only drugs and narcotics, the flashcards make it easier for beginners to learn the material. In this way, information about - Indications and mechanisms of action - Doses and available dosage forms - Instructions for use and special features can be repeated and consolidated. The new check section summarises the important side effects, interactions and contraindications. So now nothing stands in the way of successfully advising patients!

      • Trusted Partner
        2021

        Psychotropic Drugs in General Practice

        How to recognise, understand and treat patients successfully

        by PD Dr. Daniel Schüpbach and Dr. Otto Dietmaier

        The purpose of this book is to support general practitioners in finding the optimum, guideline-compliant therapy for their patients. The focus is on the clinical pictures of depression, psychosis as well as anxiety and sleep disorders and the handling of psychiatric emergencies. The reader will learn everything about the epidemiology, aetiology, diagnosis and medical treatment of these diseases, about switching therapy and about treatment in pregnancy and lactation. All the available psychotropic drugs and their pharmacological properties are described in detail – including key specific features of active substances and drug safety aspects. The table of substances in the appendix provides a clear summary of the information and simplifies the choice of the appropriate drug. The extras: - 13 factsheets with concise, summarised information to cope with tricky situations in the practice - The authors take the current treatment guidelines from Germany, Austria and Switzerland into account and name examples of proprietary medicinal products in the three countries.

      • Trusted Partner
        Humanities & Social Sciences
        September 2023

        Civil war London

        Mobilizing for parliament, 1641–5

        by Jordan S. Downs

        This book looks at London's provision of financial and military support for parliament's war against King Charles I. It explores for the first time a series of episodic, circumstantial and unique mobilisations that spanned from late 1641 to early 1645 and which ultimately led to the establishment of the New Model Army. Based on research from two-dozen archives, Civil war London charts the successes and failures of efforts to move London's vast resources and in the process poses a number of challenges to longstanding notions about the capital's 'parliamentarian' makeup. It reveals interactions between London's Corporation, parochial communities and livery companies, between preachers and parishioners and between agitators, propagandists and common people. Within these tangled webs of political engagement reside the untold stories of the movement of money and men, but also of parliament's eventual success in the English Civil War.

      • Trusted Partner
        2021

        Drugs in Pregnancy and Lactation

        Guidelines for physicians and pharmacists

        by Prof. Dr. Klaus Friese, Prof. Dr. Klaus Mörike Prof. Dr. Gerd Neumann and Dr. Wolfgang E. Paulus

        The risks in connection with the unborn child and infant when prescribing and dispensing medicinal products are adequately known. However, a sound knowledge of safety issues and precise recommendations – rather than the blanket forgoing of medicinal treatment – is crucial for providing expert, professional advice. To meet this special responsibility, a reliable source of information is essential. The now ninth edition of this standard reference work provides the necessary professional knowledge not only for all physicians and pharmacists who wish to support their pregnant and breast-feeding patients through competent advice, but also for midwives: - Information about embryonal development and developmental disorders - Well over 1000 drug substances with all important medicinal products, assessed individually - Classification according to FDA and ADEC - Differentiated risk assessment, based on current literature - Personal recommendations of the experienced and well-known team of authors from the realms of gynaecology, paediatric medicine and clinical pharmacology. The new edition contains many new assessments from current studies.

      • Trusted Partner
        Memoirs
        2022

        77 days of February. Ukraine between two symbolic dates of the Russian war ideology

        by Marichka Paplauskaite (Compiler), Authors: Inna Adrug, Anna Argirova, Kateryna Babkina, Tetyana Bezruk, Oleksandra Gorchynska, Inna Zolotukhina, Vera Kuriko, Olena Livytska, Olga Livytska, Svitlana Oslavska, Marichka Paplauskaite, Eva Raiska, Anya Semenyuk, Zoya Khramchenko, Margarita Chimyris, Iryna Yaroshynska

        As a child, she could not understand why people in films about the blockade of Leningrad were always lying down. And when Mariupol was besieged by the Russians, and she and her husband lived for many days without water, food and heat under constant shelling, she realized that when you lie down, you save strength and energy. "77 Days of February" included reports written by journalists of the Reporters media in the period between February 23 and May 9 — two symbolic dates for Russian military ideology. The invasion of Russian troops into Ukraine stopped the number of days and pushed Ukrainians back to the intervening time, where February — the month of the beginning of the great war — still lasts. In the meantime and in these candid stories, there is pain, fear, hatred, and sometimes despair. But the main thing is hope. This is a bare nerve and an honest voice of the new Ukrainian reality.

      • Trusted Partner
      • Trusted Partner
        2022

        Medication Management in the Hospital

        A workbook for ward pharmacists

        by Dr. Insa Gross, MSc Andreas Fischer and Dr. Holger Knoth

        The ward pharmacist in the hospital is like the airbag in a car. As part of a fail-safe system, they monitor and optimise the patient’s drug therapy. Ward pharmacists work hand in hand with medical and nursing staff. That situation is also reflected in this workbook. All the cases presented were patients who had been cared for, evaluated and documented by a physician-pharmacist duo or similar team with combined medical and pharmaceutical expertise. The editorial team considered it important to illustrate all critical indications typically encountered in a hospital. In assessing and selecting the examples, they were able to draw upon the many years’ experience of their pioneering work as hospital and ward pharmacists. Practical tips, checklists, comments and advice for working in the ward environment round off the individual chapters. By learning from actual cases, this book offers the unique chance to develop an instinct for the pitfalls of drug safety. That applies to those who have successfully completed further training in the field of “Medication Management in the Hospital” and for all who wish to ensure the optimum treatment for their patients through competent work in clinical pharmacy.

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