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      • Trusted Partner
        January 2020

        Ebola and Marburg Viruses, Third Edition

        by Patrick G. Guilfoile, Ph.D. and Tara C. Smith, Ph.D.

        Ebola virus and Marburg virus are related viruses that cause hemorrhagic fevers—illnesses marked by severe bleeding, organ failure, and, in many cases, death. These viruses are native to Africa, where sporadic outbreaks have occurred for decades. Ebola and Marburg Virus, Second Edition takes a look at the nature and origins of these viruses, transmission, treatment, and current vaccine research. Chapters include: A Modern Plague The Emergence of Marburg Virus Ebola in Africa and Beyond Characteristics of Filoviruses Ecology of the Viruses Detection and Treatment Developing a Vaccine Other Hemorrhagic Fevers.

      • Trusted Partner
        January 2019

        HIV/AIDS, Second Edition

        by Patrick G. Guilfoile, Ph.D.

        Human immunodeficiency virus (HIV) is a viral infection that can develop into acquired immunodeficiency syndrome (AIDS). More than 1 million Americans are infected with HIV/AIDS, and the Centers for Disease Control estimate that 15 percent of them are unaware of it. There is no cure or vaccine for HIV/AIDS, but it can be managed through proper medication and a healthy lifestyle. HIV/AIDS, Second Edition describes the symptoms, diagnosis, treatment, and prevention of HIV/AIDS, the newest research in the field, and future prospects for controlling the disease.  Chapters include: What Are HIV and AIDS? The History of HIV/AIDS The Biology of HIV/AIDS Diagnosis and Treatment of HIV/AIDS Prevention of HIV/AIDS Attempts to Develop a Vaccine for HIV/AIDS HIV/AIDS: Future Prospects and Concerns.

      • Trusted Partner
        November 2020

        One Health

        The Theory and Practice of Integrated Health Approaches

        by Jakob Zinsstag, Esther Schelling, Lisa Crump, Maxine Whittaker, Marcel Tanner, Craig Stephen

        One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.

      • Trusted Partner
        January 2021

        Anthrax, Third Edition

        by Alan Hecht, D.C.

        Anthrax became a household word in 2001 when spores of the bacterium were delivered via the U.S. Postal Service by unknown terrorists. The very mention of anthrax has the potential to set off a panic, but what is anthrax, what are its symptoms, and why is it so dangerous? Anthrax, Third Edition looks at the history of this deadly disease, from biblical times to the present, and investigates possible treatments to protect humans against it. This revised edition provides relevant, up-to-date information about anthrax and what doctors and scientists are doing to combat this threat. Chapters include: A Cloud of Death The Fifth Plague Human Anthrax Deadly Letters (Outbreak 2001) Diagnosing and Treating Anthrax Anthrax Vaccine Anthrax and Bioterrorism.

      • Trusted Partner
        November 2024

        Genetic Engineering of Vegetable Crops

        by Pritam Kalia, Donata Arena, Suresh H. Antre, Rehna Augustine, S. Backiyarani, Nikita Balyan, Rafal Baranski, Satyaprakash Barik, D. R. Bhardwaj, Vinay Bhardwaj, S.K. Chakrabarti, Supriya Chakraborty, Branca Ferdinando, Megha Ganachari, P.H. Ramanjini Gowda, Rasmieh Hamid, Vageeshbabu S. Hanura, Feba Jacob, A. Jeevalatha, Anjala K, Varsha K, S. Kalpana, Ashish Kaushal, Magdalena Klimek-Chodacka, Manoj Kumar, Polumetla Ananda Kumar, Ravinder Kumar, Aneta Lukasiewicz, DC Lakshamanareddy, T Makeshkumar, M. Malavika, Manisha Mangal, Deepu Mathew, Pallavi Mishra, Upsana Mohapatra, N. Nagesha, T.M. Ningaraju, Saurabh Pandey, Naresh Ponnam, K N Poornima, Roshini Pydi, Manoj Prasad, K. V. Ravishankar, K. Madhavi Reddy, A. T. Sadashiva, Vidya Sagar, Koushik Saha, B.G. Sangeetha, Sanjay Sathian, K.M Senthilkumar, Sanjeev Sharma, M.N. Sheela, H.K. Shreyas, B.P. Singh, Arpita Srivastav, S Sundaresha, KRM Swamy, Kamil Szymonik, Brindha T. M, Arun TS, Jagesh K. Tiwari, Shailesh K Tiwari, Simone Trecc

        Conventional plant breeding alone can no longer sustain the rising global demand for food. Genetic engineering technology makes it possible to develop new crop varieties with improved yield performance, specific quality attributes (external and internal in vegetable crops), resistance to diseases and insect pests, and environmental stresses. Genetic engineering technology for developing GM crops is complementary to genome editing and other breeding technologies. In addition to food requirements, transgenic crops have the possibility to carry edible vaccines and therapeutic proteins, to help combat human disease and malnutrition. This book reviews the importance and safety of transgenic vegetable crops and covers a wide variety of crops and different technologies. It includes: Genetic engineering in tomato, eggplant, peppers, amaranth, cauliflower, carrot, cucurbits, potato, tropical tubers and melons. Transgenic resistance to viral diseases. Embryogenic cell suspension culture. Genome editing and CRISPR/Cas9. Molecular techniques for biofortification. RNAi strategies for vegetable crop improvement. Designing futuristic vegetable crop varieties. This book is suitable for researchers in horticulture, plant science, and agricultural biotechnology as well as practitioners in vegetable breeding and seed production.

      • Trusted Partner
        January 2020

        Streptococcus (Group A), Third Edition

        by Brian R. Shmaefsky, Ph.D. and Tara C. Smith, Ph.D.

        Group A streptococci (Streptococcus pyogenes) are probably best known for causing streptococcal pharyngitis, or strep throat. But they also cause more kinds of disease than any other species of bacteria. Group A streptococci are responsible for diseases that range from mild skin conditions to scarlet fever to rheumatic fever to the devastating and sometimes deadly necrotizing fasciitis, commonly known as "flesh-eating bacteria." This revision of Streptococcus (Group A) examines the history, epidemiology, and future prospects for the ongoing battle against group A streptococci, and provides up-to-date information on research breakthroughs and the latest outbreaks of group A diseases. Updates include information on antibiotic resistance, current research on scarlet fever, and the progress on a vaccine. Chapters include: One Bacterium, Many Different Diseases Diagnosis and Treatment of the Group A Streptococcus Superficial Infections: Streptococcal Pharyngitis and Impetigo Scarlet Fever Resurgence of an Old Pathogen: Invasive Streptococcal Diseases Post-Streptococcal Complications Virulence Factors of Group A Streptococci Vaccine Prospects and the Future of the Group A Streptococcus.

      • Trusted Partner
        January 2019

        Lyme Disease, Third Edition

        by Len Yannielli and Alan Hecht, D.C.

        Lyme disease is caused by a bacterium carried by ticks. Early Lyme disease symptoms are flu-like, including fatigue, sore throat, swollen lymph glands, and neck and back pain. A red, bullseye rash can also occur. After the bacteria spreads through the body, additional symptoms may include joint and muscle pain, and meningitis, Bell's palsy, and nervous system involvement may arise. Most cases of Lyme disease can be treated with a course of antibiotics, according to the Centers for Disease Control and Prevention, and prevention includes using insect repellant and removing ticks promptly from skin and clothing. This updated edition of Lyme Disease covers the latest research about the disease, its treatment, and its effects on the human body. Chapters include: An Introduction to Lyme Disease The History of Lyme Disease The Lyme Disease Bacteria Ticks and Lyme Disease Ecology and Lyme Disease Lyme Disease Epidemiology The Tests and Treatments for Lyme Disease The Lyme Vaccine.

      • Trusted Partner
        January 2021

        Smallpox, Second Edition

        by Brian R. Shmaefsky, Ph.D. and Kim R. Finer, Ph.D.

        Before its eradication, smallpox was responsible for millions of deaths throughout history. The disease is unique to humans, caused by one of two virus variants, Variola major and Variola minor. Early symptoms include fever, fatigue, headache, muscle pain, nausea, and vomiting. After 12 to 15 days, lesions appear in the mouth, and then spread to the skin a day or two later. At this point, the disease can take several different courses. Historically, the overall fatality rate is 30%. This revised edition of Smallpox, Second Edition discusses the history and epidemiology of the disease, plus the amazing story of its eradication. Although the disease has not been seen in its natural form in more than 40 years, the future of smallpox, and its potential use as a biological weapon, are of great concern. Chapters and topics include: History of Smallpox Elimination of Smallpox Smallpox in the Americas The Smallpox Virus Symptoms Treatment Vaccine Development The Bioweapons Threat New Concerns and Future Prospects.

      • Trusted Partner
        January 2020

        Tuberculosis, Third Edition

        by Alan Hecht, D.C.

        Tuberculosis is a serious infection caused most commonly by the Mycobacterium tuberculosis bacterium or one of three other organisms of the Mycobacterium genus. Tuberculosis primarily affects the lungs, but the infection can attack any part of the body. If left untreated, tuberculosis can cause lung damage, meningitis, and even death; the World Health Organization reported 1.5 million deaths due to tuberculosis in 2018. Those at highest risk for tuberculosis include those with weakened immune systems and those in areas of the world with poor nutrition and poor access to health care. Most cases of tuberculosis can be treated with a combination of medications that are taken for several months, but failure by many people to fully follow their course of treatment has led to the emergence of drug-resistant strains of tuberculosis bacteria. Tuberculosis, Third Edition covers the history, causes, and treatments of this potentially deadly disease. Chapters include: Tuberculosis Throughout Time Robert Koch, Selman Waksman, and the Near Defeat of Tuberculosis The Tuberculosis Bacterium Consumption: What Happens Once You Become Infected Transmission from Organism to Organism The Immune Response to Tuberculosis Infection Screening for and Diagnosis of Tuberculosis The BCG Vaccine Treatment of Tuberculosis I: Sanatoriums and Early Drug Treatments Treatment of Tuberculosis II: Modern Drug Therapy The Human Immunodeficiency Virus and Tuberculosis

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        Medicine
        April 2018

        Bovine Tuberculosis

        by Mark Chambers, Stephen Gordon, Francisco Olea-Popelka, Paul Barrow

        This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals. Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease. Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.

      • Trusted Partner
        January 2020

        Streptococcus (Group B), Second Edition

        by Brian R. Shmaefsky, Ph.D. and Tara C. Smith, Ph.D.

        Group B streptococcus is a type of bacteria that mostly affects infants, the elderly, and those with immune systems compromised due to other diseases. It can cause severe infection and meningitis. Approximately 19,000 cases occur annually in the United States, and it's the most common cause of life-threatening infections in newborns. This informative book enhances readers' understanding of this disease by examining how this type of bacteria lives and is transmitted, and explaining how it can be prevented and treated. Chapters include:   History of Group B Streptococcal (GBS) Disease Group B Streptococcus (GBS) Group B Streptococcus (GBS) Diagnosis and Treatment Group B Streptococcus (GBS) with Pregnancy and Other Conditions Group B Streptococcus (GBS) Infection in Animals Group B Streptococcus (GBS) Virulence Factors Vaccine Prospects for Group B Strepotococcus (GBS)

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      • Trusted Partner
        January 2021

        Yellow Fever, Second Edition

        by Brian R. Shmaefsky, Ph.D.

        Caused by a virus that is spread through the bite of an infected mosquito, yellow fever gets its name for the jaundice it causes its victims. This hemorrhagic illness has plagued humans throughout history, and before the development of a yellow fever vaccine, the mortality rate from this disease was high. Tropical nations now prevent epidemic yellow fever levels through vaccination, and travelers to these areas are advised to take precautions. Yellow Fever, Second Edition explores both the historical and epidemiological aspects of this disease. Colorful photographs, maps, and illustrations provide important explanations of various aspects of yellow fever, and information on vaccination, treatment, prevention, and up-to-date statistics on worldwide incidences are provided. Chapters include: The Yellow Fever Disease Disease Course and Epidemiology Diagnosis, Treatment, and Prevention Yellow Fever and Other Modern Plagues The Impact of Diseases on History Future Directions in Controlling Viral Diseases.

      • Trusted Partner
        January 2019

        Mumps

        by Alan Hecht, D.C.

        Once a common childhood illness, mumps, also known as epidemic parotitis, has become less frequent since the development of an effective vaccine that has greatly diminished the occurrence of the disease in the United States. Even with the mumps vaccination program, however, outbreaks of mumps continue to occur throughout the United States. Many nations do not have an effective mumps vaccination program, and infants, children, and young adults in these locations are at risk for developing not only viral meningitis from the mumps virus but other complications following infection, including inflammation of the testes and ovaries, pancreatitis, myocarditis (inflammation of the heart muscle), and deafness. Mumps covers the history of the disease, its current treatment, its prevention, and the forecasts for controlling mumps worldwide. Chapters and topics include: An Overview of Mumps The History of Mumps The Mumps Virus Epidemiology of Mumps Mumps Symptoms, Diagnosis, and Complications Treatment and Prevention of Mumps The Future of Mumps.

      • Trusted Partner
        January 2020

        Chicken Pox, Second Edition

        by Patrick Guilfoile, Ph.D.

        Until relatively recently, chicken pox was a rite of passage for children and was often looked upon as just a nuisance, although this illness can cause complications in some people. Though the development and use of a chicken pox vaccine has reduced the number of chicken pox cases, the unvaccinated remain vulnerable. In addition, shingles, a painful condition that can arise after an initial chicken pox infection, is a concern, particularly in older people. Chicken Pox, Second Edition presents an overview of this disease caused by a herpesvirus known as the varicella-zoster virus, explaining the signs and symptoms of the disease, how it spreads, how it is treated, and how the development of a vaccine has affected the incidence of chicken pox.  Chapters include: What Is Chicken Pox? The History of Chicken Pox Chicken Pox in Young Children Chicken Pox in Infants and Adults How Is Chicken Pox Diagnosed and Treated? How Is Chicken Pox Prevented? What Is Shingles? The Future of Chicken Pox and Shingles.

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        Biology, life sciences
        October 2014

        Plant-derived Pharmaceuticals

        Principles and Applications for Developing Countries

        by Rima Menassa, Karen McDonald, Shawn Chen, Inga Hitzeroth, Gregory Pogue, Pascal Drake, Andreas Günter Lössl, M A D'Aoust, David Aviezer, Elizabeth Loza Rubio, John Howard, Carla Marusic, Somen Nandi. Edited by Kathleen L. Hefferon.

        Describing recent developments in the engineering and generation of plants as production platforms for biopharmaceuticals, this book includes both vaccines and monoclonal antibodies. It has a particular emphasis on targeting diseases which predominate in less developed countries, encompassing the current state of technologies and describing expression systems and applications. This book also includes a variety of vaccine case studies, protecting against pervasive infectious diseases such as rabies, influenza and HIV.

      • Trusted Partner
        Science & Mathematics
        September 2019

        Plant-derived Pharmaceuticals

        Principles and Applications for Developing Countries

        by Kathleen L. Hefferon

        Describing recent developments in the engineering and generation of plants as production platforms for biopharmaceuticals, this book includes both vaccines and monoclonal antibodies. It has a particular emphasis on targeting diseases which predominate in less developed countries, encompassing the current state of technologies and describing expression systems and applications. This book also includes a variety of vaccine case studies, protecting against pervasive infectious diseases such as rabies, influenza and HIV.

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