June 2000
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MedicineDecember 2016Antimicrobial Stewardship
Principles and Practice
by Kerry LaPlante, Cheston Cunha, Haley Morrill, Louis Rice, Eletherios Mylonakis
In an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration. ; Antimicrobial research has hit a wall: treatment discoveries are rarer and resistant pathogen strains more prevalent. Rather than infection control itself, antimicrobial stewardship is an essential measure in ensuring management of hospital-acquired infections. Throughout this book, international experts discuss all angles of stewardship. ; Part I: Overview of Antibiotic StewardshipCh.1: Principles of Antimicrobial StewardshipCh 2: Clinical Perspective of Antimicrobial StewardshipCh 3: History of Antimicrobial StewardshipCh 4: The Importance of Education in Antimicrobial StewardshipPart II: Antibiotic Resistance Principles in Antibiotic Stewardship Ch 5: Intrinsic and Acquired Mechanisms of ResistanceCh 6: Antimicrobial Resistance: Selection vs. InductionCh 7: Colonization and its importance for emergence of clinical resistanceCh 8: Antibiotic Resistance: associations and implications for antibiotic usage strategies to control multi-resistant bacteriaPart III: Microbiology Laboratory Role in Antibiotic StewardshipCh 9: The role of active surveillance in the prevention of healthcare-acquired infections and antibiotic stewardshipCh 10: Role of Antibiogram in Antibiotic StewardshipCh 11: Selective Reporting and Antimicrobial StewardshipCh 12: Role of New Diagnostics to Enhance Antibiotic Stewardship EffortsPart IV: Infection Control Aspects of Antibiotic StewardshipCh 13: Epidemiology of S aureus and enterococci in children and an overview of antimicrobial resistanceCh 14: Epidemiology of multi-drug resistant gram-negative organismsCh 15: Pathogenesis and Epidemiology of Clostridium difficile Infection: Implications for Antibiotic StewardshipCh 16: Role of the Hospital Epidemiologist in Supporting Antimicrobial StewardshipPart V: Pharmacokinetic (PK) & Pharmacodynamic (PD) Aspects of Antibiotic Dosing in Antibiotic StewardshipCh 17: Principles of Pharmacokinetic / Pharmacodynamic Optimization for Antibiotic DosingCh 18: Optimal use of Gram-negative antibiotics in the real world: providing effective therapy while minimizing resistanceCh19: Optimal Use of FluoroquinolonesCh 20: Optimal Use of Beta-lactam AntibioticsCh 21: Current Approach to Optimal Use and Dosing of Vancomycin in Adult PatientsCh 22: Principles of IV to PO SwitchPart VI: Pharmacy Department Role in Antibiotic StewardshipCh 23: Role of Pharmacists in Antimicrobial StewardshipCh 24: Formulary Management and Economic Considerations; Bridging the Gap between Quality Care and CostCh 25: Approaches in benchmarkingCh 26: Development and execution of stewardship interventionsCh 27: Technologic support for antimicrobial stewardshipPart VII: Measuring Outcomes in Antibiotic Stewardship ProgramsCh 28: Role of Guidelines and Statistical Milestones for Antimicrobial StewardshipCh 29: Economic considerations of Antimicrobial Stewardship ProgramsCh 30: Pharmacoeconomic Implications of Antimicrobial Adverse EventsCh 31: Antimicrobial stewardship programs in areas of increased pathogen resistancePart VIII: Antimicrobial Stewardship and Various Practice SitesCh 32: Role of Antimicrobial Stewardship in PediatricsCh 33: Antimicrobial Stewardship in the Intensive Care UnitCh 34: Role of Antimicrobial Stewardship in a Community HospitalCh 35: Outpatient Parenteral Antimicrobial Therapy (OPAT)Ch 36: The Importance of Interdisciplinary Collaboration in Antimicrobial Stewardship: Immersion of Future Healthcare ProfessionalsCh 37: Antimicrobial Stewardship and the Importance of Working with the Government and Pharmaceutical IndustryCh 38: Hospitalist Perspective on the Role of Antimicrobial Stewardship
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September 2024Arthropod Management and Landscape Considerations in Large-Scale Agroecosystems
by Michael J Brewer, Gary L. Hein, Kristen Baum, Mahendra Bhandari, Haley Butler, Hannalene du Plessis, Norman C. Elliott, Peter C Ellsworth, Sarah Elzay, Isaac L. Esquivel, Ashleigh M. Faris, Aaron J. Gassmann, Kristopher L Giles, Maura Hall, Louis S. Hesler, Anders S. Huseth, William D. Hutchison, Ian MacRae, Robert L. Meagher, Jr, Lance J. Meinke, Steven E. Naranjo, Matthew O'Neal, Shannon L. Osborne, Pankaj Pal, Katherine A. Parys, Dominic Reisig, Tom A Royer, Nina Rudin, Thomas W. Sappington, Gregory A. Sword, Ashley E. Tessnow, Paul A. Umina, Johnnie van den Berg
For large-scale agroecosystems, patterns of pest population increases (graded increases or abrupt outbreaks) and declines (graded suppression or abrupt crashes) vary considerably and are influenced by factors within crop fields and across broader landscape scales. Better understanding of pest population dynamics and the implications of spatial interactions on the function and development of pest management approaches are the main themes of this important book. The book builds from a 60+ year history of field-based pest management by focusing on the drivers of pest management in large-scale agroecosystems and the landscape-scale processes that affect these drivers and contribute to variation in pest outbreaks and suppression. These drivers include abiotic and biotic influences such as weather, spatial composition and arrangement of landscape elements, and widely applied managed inputs such as planting and crop rotation schedules, crop varietal selection, and land and soil conservation efforts. The book introduces general concepts, opportunities, and challenges of arthropod management in large-scale agroecosystems. Case studies from major field crop-based agroecosystems are used to present research approaches and improve understanding and management of pest and beneficial insects in large-scale agroecosystems. Specific research findings are provided on multi-trophic interactions within the system as influenced by climate, landscape, and other ecological, agricultural, and social/economic components of the agroecosystem. The book concludes with a synthesis of these concepts and prospectus for future research and developments in arthropod management in large-scale, plant-based agroecosystems. The book is essential reading for researchers in applied entomology and ecology and for pest management practitioners.
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March 2024Mayfair House
Oben lädt Madam zum Ball der Saison, unten planen die Dienstmädchen den Raub des Jahrhunderts
by Alex Hay
London, Mayfair 1905: Die Villa der Familie de Vries ist die prachtvollste auf der Park Lane, außen weißer Marmor, innen kostbare Möbel, funkelnde Kronleuchter, Kristallschalen und edle Kunstgegenstände, Silber und Gold glänzen um die Wette. Es ist Mrs Kings ganzer Stolz, für die exzellente Haushaltsführung der noblen Residenz zu sorgen – bis sie beim Tod des Hausherrn nach Jahren treuer Dienste kurzerhand entlassen wird. Doch Mrs King denkt gar nicht daran, sich der Willkür der Erbin de Vries zu fügen. Sie will nur eins – Gerechtigkeit. Mit einer bunten Truppe von Komplizinnen plant sie den Coup ihres Lebens: In der Nacht des großen Kostümballs werden sie unter den Augen der vornehmen Gäste das Haus bis auf den letzten Silberlöffel ausräumen. Und während sich im Obergeschoss die High Society amüsiert, beginnt ein Stockwerk tiefer der kühnste Raubüberfall, den London je gesehen hat … Alex Hay erzählt in diesem Heist-Roman voller Eleganz und Esprit die Geschichte eines atemberaubenden Rachefeldzugs und einer schillernden Gruppe Frauen, die sich nehmen, was ihnen zusteht.
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Logik – ein Anfängerkurs
by Alex Blum
Logik – ein Anfängerkurs - von Alex Blum Ein umfassender Anfängerkurs in Logik für Studenten der Philosophie. Der Autor will eine natürliche Deduktionstechnik und ein eingehendes und intuitives Verständnis der Metatheorie der elementaren Logik vermitteln. Professor Dr. Alex Blum ist einer der führenden Logiker Israels und hat bereits zahlreiche Artikel in internationalen Zeitschriften veröffentlicht. Er ist Professor Emeritus der Philosophie, Bar-Ilan Universität bei Tel Aviv. Rechte für die deutsche Ausgabe und andere Sprachen sind noch erhältlich!
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March 2024Mayfair House
Oben lädt Madam zum Ball der Saison, unten planen die Dienstmädchen den Raub des Jahrhunderts
by Alex Hay, Regina Rawlinson
London, Mayfair 1905: Die Villa der Familie de Vries ist die prachtvollste auf der Park Lane, außen weißer Marmor, innen kostbare Möbel, funkelnde Kronleuchter, Kristallschalen und edle Kunstgegenstände, Silber und Gold glänzen um die Wette. Es ist Mrs Kings ganzer Stolz, für die exzellente Haushaltsführung der noblen Residenz zu sorgen – bis sie beim Tod des Hausherrn nach Jahren treuer Dienste kurzerhand entlassen wird. Doch Mrs King denkt gar nicht daran, sich der Willkür der Erbin de Vries zu fügen. Sie will nur eins – Gerechtigkeit. Mit einer bunten Truppe von Komplizinnen plant sie den Coup ihres Lebens: In der Nacht des großen Kostümballs werden sie unter den Augen der vornehmen Gäste das Haus bis auf den letzten Silberlöffel ausräumen. Und während sich im Obergeschoss die High Society amüsiert, beginnt ein Stockwerk tiefer der kühnste Raubüberfall, den London je gesehen hat … Alex Hay erzählt in diesem Heist-Roman voller Eleganz und Esprit die Geschichte eines atemberaubenden Rachefeldzugs und einer schillernden Gruppe Frauen, die sich nehmen, was ihnen zusteht.
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La Logique
by Pr. Alex Blum
La Logique, par le Pr. Alex Blum Un cours systématique de logique de premier niveau (2 volumes) pour les étudiants en philosophie. Ce livre présente une technique de déduction naturelle, et donne une compréhension intuitive et minutieuse de la métathéorie de logique élémentaire. Professeur Blum, l’un des plus éminents logiciens philosophiques, enseigne au département de philosophie de l’Université Bar-Ilan, en Israël.
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Children's & YASilver Flood (1). The Mystery of Ray´s Rock
by Alex Falkner/ Torben Weit
The seven children are completely cut off from civilisation, mobile phones don’t work anymore and there’s no sign of help. Strange things happen on the island. Plants and animals grow unnaturally fast, their supplies are raided ... And as other groups of school children emerge, a life and death race begins for Eddie, Milla and their classmates to be rescued from the island. The first instalment of the ‘Silver Flood’ duology: a dangerous adventure with exciting plot twists and scare-factor. For all readers of survival and adventure stories aged 10+. Fast-paced reading for boys and girls, for outdoor kids and all those on their way! The final volume 2, GONE MISSING ON RAY’S ROCK, will be published on 7th April 2020!
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July 2024Biological Control Programmes in Canada, 2013-2023
by Meghan A. Vankosky, Veronique Martel, Paul K. Abram, Susanna Acheampong, Patrice Audy, Jacob V. Basso, Tracey Baute, Roger L. Becker, Koïchi Beltrando, Andrew M.R. Bennett, Jonathan Bernardo-Santos, Suzanne E. Blatt, Michael K. Bomford, Sébastien Boquel, Patrice Bouchard, Robert S. Bourchier, Susan M. Boyetchko, Andrea M. Brauner, Jacques Brodeur, Luc Brodeur, Rosemarije Buitenhuis, Erin Bullas-Appleton, Naomi Cappuccino, Juli Carrillo, Allan L. Carroll, Haley Catton, Daniel Cormier, Ghislaine Cortat, Jenny S. Cory, Joan E. Cossentine, Isabelle Couture, Massimo Cristofaro, Rosemarie De Clerck-Floate, Carly A. Demers, Pauline S. Deschodt, Peggy L. Dixon, Josée Doyon, Shelby V. Dufton, Tim J Dumonceaux, François Dumont, Marianne Elliott, David J. Ensing, Nadir Erbilgin, Maya Evenden, Diana Catalina Fernandez, José L. Fernández-Triana, Jeffrey G. Fidgen, Annabelle Firlej, Kevin D. Floate, Anne-Marie Fortier, François Fournier, Marc Fournier, Michelle T. Franklin, Annie-Ève Gagnon, Bruno G
Biological control is an important component of integrated and ecological pest management programmes. Its importance continues to increase as plant protection is challenged with climate change, invasive species, pesticide resistance, de-registration of pesticide active ingredients, and increasing consumer demands for sustainably produced food and fibre. Biological control is highly compatible with organic cropping systems and evolving pest management frameworks, including biovigilance. Canada continues to be a world leader in biological control research, development of biological control policy, and implementation of biological control programmes. This is the sixth volume of a series of books reporting on the status of biological control research and on biological control programmes employed in Canada. This volume features 58 case study chapters that describe the research and progress in implementation of biological control for pests including insects, mites, weeds, and plant pathogens. Topics important to biological control, including policy, emerging technologies, biological control in urban landscapes and future targets for biological control are reviewed. Although the volume focusses on the Canadian biological control experience, the chapters will be of interest to a global audience of researchers and students of biological control, risk assessment, ecology, and pest management. This book Offers a detailed analysis of the state-of-the-art of biological control in Canada. Explains how biological control research is responding to challenges including climate change and invasive alien species. Gives insights in effective risk assessment and pest management. It is a valuable resource for students and researchers of pest management and biological control, and for practitioners and policy-makers needing analysis of the practical implications of using this approach.
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April 2020Silberflut (2). Die Verschollenen von Ray’s Rock
by Falkner, Alex
Pass auf! Denn die Silberflut erwischt auch dich! Keine Rettung weit und breit! Eddie, Milla und die anderen sitzen auf Ray’s Rock fest - mehr denn je, nachdem der Kampf um das Motorboot unwiederbringlich verloren ist. Die Geschehnisse auf der Insel werden immer unheimlicher: Seltsame Lichter flackern durch die Nacht und wilde Tiere scheinen auf ihren nächtlichen Streifzügen engere Kreise um das Camp zu ziehen. Als auch noch Eddies bester Kumpel Nick verschwindet, wird klar: Auf Ray’s Rock ist keiner von ihnen sicher … Der zweite und finale Band der „Silberflut“-Dilogie: Ein gefährliches Abenteuer mit spannenden Twists und Gruselfaktor. Für alle Leser von Survival- und Abenteuergeschichten ab 10. Rasantes Lesefutter für Jungen und Mädchen, für Outdoor-Kids und alle, die es noch werden wollen! Die Bücher der „Silberflut“-Dilogie: Band 1: „Das Geheimnis von Ray’s Rock“ Band 2: „Die Verschollenen von Ray’s Rock“
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September 2005Alex, Dafi und ich
Roman über die Freundschaft
by Almagor, Gila / Übersetzt von Mirjam, Pressler
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Literature & Literary StudiesApril 2023Charles Dickens and Georgina Hogarth
A curious and enduring relationship
by Christine Skelton
Charles Dickens called his sister-in-law Georgina Hogarth his 'best and truest friend'. Georgina saw Dickens as much more than a friend. They lived together for twenty-eight years, during which time their relationship constantly changed. The sister of his wife Catherine, the sharp and witty Georgina moved into the Dickens home aged fifteen. What began as a father-daughter relationship blossomed into a genuine rapport, but their easy relations were fractured when Dickens had a mid-life crisis and determined to rid himself of Catherine. Georgina's refusal to leave Dickens and his desire for her to remain in his household led to rumours of an affair and even illegitimate children. He left her the equivalent of almost £1 million and all his personal papers in his will. Georgina's commitment to Dickens was unwavering but it is far from clear what he did to deserve such loyalty. There were several occasions when he misused her in order to protect his public reputation. Why did Georgina betray her once much-loved sister? Why did she fall out with her family and risk her reputation in order to stay with Dickens? And why did the Dickenses' daughter Katey say it was 'the greatest mistake ever' to invite a sister-in-law to live with a family?
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Literature & Literary StudiesApril 2020Interweaving myths in Shakespeare and his contemporaries
by Janice Valls-Russell, Agnès Lafont, Charlotte Coffin
This volume proposes new insights into the uses of classical mythology by Shakespeare and his contemporaries, focusing on interweaving processes in early modern appropriations of myth. Its 11 essays show how early modern writing intertwines diverse myths and plays with variant versions of individual myths that derive from multiple classical sources, as well as medieval, Tudor and early modern retellings and translations. Works discussed include poems and plays by William Shakespeare, Christopher Marlowe and others. Essays concentrate on specific plays including The Merchant of Venice and Dido Queen of Carthage, tracing interactions between myths, chronicles, the Bible and contemporary genres. Mythological figures are considered to demonstrate how the weaving together of sources deconstructs gendered representations. New meanings emerge from these readings, which open up methodological perspectives on multi-textuality, artistic appropriation and cultural hybridity.
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June 2024Dark Scar
A psychological Thriller. Dr. Evelin Wolf and Alex Gutenberg 2
by Roxann Hill, Paul Wagle, Rebecca Steinberg, John Julian, Nicholas Mockridge, Alexios Saskalidis
Death lurks in the shadows Who are you? Hamburg Criminal Psychologist Dr. Evelin Wolf wonders as she examines the severely disturbed homeless man with the conspicuous scar across his face. The extremely aggressive man with no memory or identity is alleged to have committed a brutal murder. But Evelin and Assistant District Attorney Alex Gutenberg doubt his guilt and suspect there is something more behind the supposedly crystal-clear case. Shortly thereafter, Hamburg is shaken by a series of murders unparalleled in cruelty and sadism. The perverted killer draws a bloody trail across the Hanseatic city and links it with a clear message to Alex and Evelin: Revenge. Alex and Evelin work feverishly to solve both cases. In the process, they make a fatal mistake. And the killer exploits it mercilessly…
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May 2024Moonslaughter
A psychological Thriller. Dr. Evelin Wolf and Alex Gutenberg 1
by Roxann Hill, Paul Wagle, Rebecca Steinberg, John Julian, Nicholas Mockridge, LiveLive Media GmbH, Torsten Schwiemann, Alexios Saskalidis
Some deserve to live. Others deserve to die. A lunar eclipse hovers above Hamburg and bathes houses and streets in an unearthly light. In the exclusive district of Blankenese, four men are brutally murdered in the basement of a villa. Only the granddaughter of the owner survives the bloody massacre. Severely traumatized and completely listless, she is found sitting in the middle of the corpses. She cannot remember anything. Assistant District Attorney Alex Gutenberg, who has to struggle with a number of personal issues himself, asks the criminal psychologist Dr. Evelin Wolf for support. When Evelin succeeds in penetrating the buried memories of the key witness piece by piece, she and Alex begin to disclose not only the motives for the massacre, but also the unimaginable extent of cruelty and depravity behind it. And Alex suddenly finds himself confronted with his own guilt-ridden past...
