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MedicineDecember 2016Antimicrobial Stewardship
Principles and Practice
by Kerry LaPlante, Cheston Cunha, Haley Morrill, Louis Rice, Eletherios Mylonakis
In an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration. ; Antimicrobial research has hit a wall: treatment discoveries are rarer and resistant pathogen strains more prevalent. Rather than infection control itself, antimicrobial stewardship is an essential measure in ensuring management of hospital-acquired infections. Throughout this book, international experts discuss all angles of stewardship. ; Part I: Overview of Antibiotic StewardshipCh.1: Principles of Antimicrobial StewardshipCh 2: Clinical Perspective of Antimicrobial StewardshipCh 3: History of Antimicrobial StewardshipCh 4: The Importance of Education in Antimicrobial StewardshipPart II: Antibiotic Resistance Principles in Antibiotic Stewardship Ch 5: Intrinsic and Acquired Mechanisms of ResistanceCh 6: Antimicrobial Resistance: Selection vs. InductionCh 7: Colonization and its importance for emergence of clinical resistanceCh 8: Antibiotic Resistance: associations and implications for antibiotic usage strategies to control multi-resistant bacteriaPart III: Microbiology Laboratory Role in Antibiotic StewardshipCh 9: The role of active surveillance in the prevention of healthcare-acquired infections and antibiotic stewardshipCh 10: Role of Antibiogram in Antibiotic StewardshipCh 11: Selective Reporting and Antimicrobial StewardshipCh 12: Role of New Diagnostics to Enhance Antibiotic Stewardship EffortsPart IV: Infection Control Aspects of Antibiotic StewardshipCh 13: Epidemiology of S aureus and enterococci in children and an overview of antimicrobial resistanceCh 14: Epidemiology of multi-drug resistant gram-negative organismsCh 15: Pathogenesis and Epidemiology of Clostridium difficile Infection: Implications for Antibiotic StewardshipCh 16: Role of the Hospital Epidemiologist in Supporting Antimicrobial StewardshipPart V: Pharmacokinetic (PK) & Pharmacodynamic (PD) Aspects of Antibiotic Dosing in Antibiotic StewardshipCh 17: Principles of Pharmacokinetic / Pharmacodynamic Optimization for Antibiotic DosingCh 18: Optimal use of Gram-negative antibiotics in the real world: providing effective therapy while minimizing resistanceCh19: Optimal Use of FluoroquinolonesCh 20: Optimal Use of Beta-lactam AntibioticsCh 21: Current Approach to Optimal Use and Dosing of Vancomycin in Adult PatientsCh 22: Principles of IV to PO SwitchPart VI: Pharmacy Department Role in Antibiotic StewardshipCh 23: Role of Pharmacists in Antimicrobial StewardshipCh 24: Formulary Management and Economic Considerations; Bridging the Gap between Quality Care and CostCh 25: Approaches in benchmarkingCh 26: Development and execution of stewardship interventionsCh 27: Technologic support for antimicrobial stewardshipPart VII: Measuring Outcomes in Antibiotic Stewardship ProgramsCh 28: Role of Guidelines and Statistical Milestones for Antimicrobial StewardshipCh 29: Economic considerations of Antimicrobial Stewardship ProgramsCh 30: Pharmacoeconomic Implications of Antimicrobial Adverse EventsCh 31: Antimicrobial stewardship programs in areas of increased pathogen resistancePart VIII: Antimicrobial Stewardship and Various Practice SitesCh 32: Role of Antimicrobial Stewardship in PediatricsCh 33: Antimicrobial Stewardship in the Intensive Care UnitCh 34: Role of Antimicrobial Stewardship in a Community HospitalCh 35: Outpatient Parenteral Antimicrobial Therapy (OPAT)Ch 36: The Importance of Interdisciplinary Collaboration in Antimicrobial Stewardship: Immersion of Future Healthcare ProfessionalsCh 37: Antimicrobial Stewardship and the Importance of Working with the Government and Pharmaceutical IndustryCh 38: Hospitalist Perspective on the Role of Antimicrobial Stewardship
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March 2024Mayfair House
Oben lädt Madam zum Ball der Saison, unten planen die Dienstmädchen den Raub des Jahrhunderts
by Alex Hay
London, Mayfair 1905: Die Villa der Familie de Vries ist die prachtvollste auf der Park Lane, außen weißer Marmor, innen kostbare Möbel, funkelnde Kronleuchter, Kristallschalen und edle Kunstgegenstände, Silber und Gold glänzen um die Wette. Es ist Mrs Kings ganzer Stolz, für die exzellente Haushaltsführung der noblen Residenz zu sorgen – bis sie beim Tod des Hausherrn nach Jahren treuer Dienste kurzerhand entlassen wird. Doch Mrs King denkt gar nicht daran, sich der Willkür der Erbin de Vries zu fügen. Sie will nur eins – Gerechtigkeit. Mit einer bunten Truppe von Komplizinnen plant sie den Coup ihres Lebens: In der Nacht des großen Kostümballs werden sie unter den Augen der vornehmen Gäste das Haus bis auf den letzten Silberlöffel ausräumen. Und während sich im Obergeschoss die High Society amüsiert, beginnt ein Stockwerk tiefer der kühnste Raubüberfall, den London je gesehen hat … Alex Hay erzählt in diesem Heist-Roman voller Eleganz und Esprit die Geschichte eines atemberaubenden Rachefeldzugs und einer schillernden Gruppe Frauen, die sich nehmen, was ihnen zusteht.
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Logik – ein Anfängerkurs
by Alex Blum
Logik – ein Anfängerkurs - von Alex Blum Ein umfassender Anfängerkurs in Logik für Studenten der Philosophie. Der Autor will eine natürliche Deduktionstechnik und ein eingehendes und intuitives Verständnis der Metatheorie der elementaren Logik vermitteln. Professor Dr. Alex Blum ist einer der führenden Logiker Israels und hat bereits zahlreiche Artikel in internationalen Zeitschriften veröffentlicht. Er ist Professor Emeritus der Philosophie, Bar-Ilan Universität bei Tel Aviv. Rechte für die deutsche Ausgabe und andere Sprachen sind noch erhältlich!
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March 2024Mayfair House
Oben lädt Madam zum Ball der Saison, unten planen die Dienstmädchen den Raub des Jahrhunderts
by Alex Hay, Regina Rawlinson
London, Mayfair 1905: Die Villa der Familie de Vries ist die prachtvollste auf der Park Lane, außen weißer Marmor, innen kostbare Möbel, funkelnde Kronleuchter, Kristallschalen und edle Kunstgegenstände, Silber und Gold glänzen um die Wette. Es ist Mrs Kings ganzer Stolz, für die exzellente Haushaltsführung der noblen Residenz zu sorgen – bis sie beim Tod des Hausherrn nach Jahren treuer Dienste kurzerhand entlassen wird. Doch Mrs King denkt gar nicht daran, sich der Willkür der Erbin de Vries zu fügen. Sie will nur eins – Gerechtigkeit. Mit einer bunten Truppe von Komplizinnen plant sie den Coup ihres Lebens: In der Nacht des großen Kostümballs werden sie unter den Augen der vornehmen Gäste das Haus bis auf den letzten Silberlöffel ausräumen. Und während sich im Obergeschoss die High Society amüsiert, beginnt ein Stockwerk tiefer der kühnste Raubüberfall, den London je gesehen hat … Alex Hay erzählt in diesem Heist-Roman voller Eleganz und Esprit die Geschichte eines atemberaubenden Rachefeldzugs und einer schillernden Gruppe Frauen, die sich nehmen, was ihnen zusteht.
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La Logique
by Pr. Alex Blum
La Logique, par le Pr. Alex Blum Un cours systématique de logique de premier niveau (2 volumes) pour les étudiants en philosophie. Ce livre présente une technique de déduction naturelle, et donne une compréhension intuitive et minutieuse de la métathéorie de logique élémentaire. Professeur Blum, l’un des plus éminents logiciens philosophiques, enseigne au département de philosophie de l’Université Bar-Ilan, en Israël.
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Children's & YASilver Flood (1). The Mystery of Ray´s Rock
by Alex Falkner/ Torben Weit
The seven children are completely cut off from civilisation, mobile phones don’t work anymore and there’s no sign of help. Strange things happen on the island. Plants and animals grow unnaturally fast, their supplies are raided ... And as other groups of school children emerge, a life and death race begins for Eddie, Milla and their classmates to be rescued from the island. The first instalment of the ‘Silver Flood’ duology: a dangerous adventure with exciting plot twists and scare-factor. For all readers of survival and adventure stories aged 10+. Fast-paced reading for boys and girls, for outdoor kids and all those on their way! The final volume 2, GONE MISSING ON RAY’S ROCK, will be published on 7th April 2020!
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April 2020Silberflut (2). Die Verschollenen von Ray’s Rock
by Falkner, Alex
Pass auf! Denn die Silberflut erwischt auch dich! Keine Rettung weit und breit! Eddie, Milla und die anderen sitzen auf Ray’s Rock fest - mehr denn je, nachdem der Kampf um das Motorboot unwiederbringlich verloren ist. Die Geschehnisse auf der Insel werden immer unheimlicher: Seltsame Lichter flackern durch die Nacht und wilde Tiere scheinen auf ihren nächtlichen Streifzügen engere Kreise um das Camp zu ziehen. Als auch noch Eddies bester Kumpel Nick verschwindet, wird klar: Auf Ray’s Rock ist keiner von ihnen sicher … Der zweite und finale Band der „Silberflut“-Dilogie: Ein gefährliches Abenteuer mit spannenden Twists und Gruselfaktor. Für alle Leser von Survival- und Abenteuergeschichten ab 10. Rasantes Lesefutter für Jungen und Mädchen, für Outdoor-Kids und alle, die es noch werden wollen! Die Bücher der „Silberflut“-Dilogie: Band 1: „Das Geheimnis von Ray’s Rock“ Band 2: „Die Verschollenen von Ray’s Rock“
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September 2005Alex, Dafi und ich
Roman über die Freundschaft
by Almagor, Gila / Übersetzt von Mirjam, Pressler
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Literature & Literary StudiesApril 2023Charles Dickens and Georgina Hogarth
A curious and enduring relationship
by Christine Skelton
Charles Dickens called his sister-in-law Georgina Hogarth his 'best and truest friend'. Georgina saw Dickens as much more than a friend. They lived together for twenty-eight years, during which time their relationship constantly changed. The sister of his wife Catherine, the sharp and witty Georgina moved into the Dickens home aged fifteen. What began as a father-daughter relationship blossomed into a genuine rapport, but their easy relations were fractured when Dickens had a mid-life crisis and determined to rid himself of Catherine. Georgina's refusal to leave Dickens and his desire for her to remain in his household led to rumours of an affair and even illegitimate children. He left her the equivalent of almost £1 million and all his personal papers in his will. Georgina's commitment to Dickens was unwavering but it is far from clear what he did to deserve such loyalty. There were several occasions when he misused her in order to protect his public reputation. Why did Georgina betray her once much-loved sister? Why did she fall out with her family and risk her reputation in order to stay with Dickens? And why did the Dickenses' daughter Katey say it was 'the greatest mistake ever' to invite a sister-in-law to live with a family?
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Literature & Literary StudiesApril 2020Interweaving myths in Shakespeare and his contemporaries
by Janice Valls-Russell, Agnès Lafont, Charlotte Coffin
This volume proposes new insights into the uses of classical mythology by Shakespeare and his contemporaries, focusing on interweaving processes in early modern appropriations of myth. Its 11 essays show how early modern writing intertwines diverse myths and plays with variant versions of individual myths that derive from multiple classical sources, as well as medieval, Tudor and early modern retellings and translations. Works discussed include poems and plays by William Shakespeare, Christopher Marlowe and others. Essays concentrate on specific plays including The Merchant of Venice and Dido Queen of Carthage, tracing interactions between myths, chronicles, the Bible and contemporary genres. Mythological figures are considered to demonstrate how the weaving together of sources deconstructs gendered representations. New meanings emerge from these readings, which open up methodological perspectives on multi-textuality, artistic appropriation and cultural hybridity.
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Literature & Literary StudiesApril 2021John Derricke's The Image of Irelande: with a Discoverie of Woodkarne
by Thomas Herron, Denna Iammarino, Maryclaire Moroney, Joshua Samuel Reid
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Literature & Literary StudiesMay 2024David, Donne and Thirsty Deer
Selected Essays of Anne Lake Prescott
by Anne Lake Prescott, Roger Kuin, William A. Oram
For nearly half a century Anne Lake Prescott has been a force and an inspiration in Renaissance studies. A force, because of her unique blend of learning and wit and an inspiration through her tireless encouragement of younger scholars and students. Her passion has always been the invisible bridge across the Channel: the complex of relations, literary and political, between Britain and France. The essays in this long-awaited collection range from Edmund Spenser to John Donne, from Clément Marot to Pierre de Ronsard. Prescott has a particular fondness for King David, who appears several times; and the reader will encounter chessmen, bishops, male lesbian voices and Roman whores. Always Prescott's immense erudition is accompanied by a sly and gentle wit that invites readers to share her amusement. Reading her is a joyful education.
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