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      • Trusted Partner
        Gene Flow
        Science & Mathematics
        November 2021

        Gene Flow

        Monitoring, Modeling and Mitigation

        by Wei Wei, Neal Stewart

        Gene flow is a natural process that occurs spontaneously and enables the evolution of life. However, with the release of genetically modified organisms, concerns have focused on introduced foreign transgenes and their dispersal in nature through gene flow. This book examines gene flow of transgenes, such as herbicide resistance genes, with the goal of understanding the factors that may affect the process of gene flow. A greater biological understanding is essential to make sound management regulatory decisions when also taking into consideration the processes that happen in conventional plants. Monitoring, modelling, and mitigation are the three most closely related elements of gene flow. The book includes both scientific reviews and perspectives on gene flow and experimental case studies, including studies of gene flow in soybean and poplar. The authors present diverse views and research methodologies to understand transgene flow. This book: Focuses on applications of gene flow (monitoring, modelling, and mitigation); Includes both review chapters and case studies; Is written by international team of scientists currently working in gene flow. This book will be valuable for students and researchers in genetics, biotechnology, plant science, and environmental science. It also provides key insights of value to regulators of biotechnology as well as policy-makers.

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      • Trusted Partner
        Transgenic Insects
        Science & Mathematics
        May 2022

        Transgenic Insects

        Techniques and Applications

        by Mark Quentin Benedict, Maxwell Scott

        Technology for modifying the genotypes and phenotypes of insects and other arthropods has steadily progressed by development of more precise and powerful methods, most prominently transgenic modification. There is now almost unlimited ability to modify phenotypes to benefit human health and agriculture. Precise DNA modifications and gene drive particularly have the power to make wild-type populations less harmful in ways that could never be performed with previous transgenic approaches. This transition from primarily laboratory science to greater prominence for field applications has also necessitated a greater development of modelling, ethical considerations and regulatory oversight. The 2nd edition of Transgenic Insects contains chapters contributed by experts in the field that cover the technology and applications that are now possible. These include an increased emphasis on acceptance issues that will be necessary for application of many technologies.

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      • Trusted Partner
        Das Auge der Pyramide
        November 1997

        Das Auge der Pyramide

        by Shea, Robert; Wilson, Robert A. / Deutsch Breger, Udo

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      • Trusted Partner
        Plant Gene Silencing
        Science & Mathematics
        May 2017

        Plant Gene Silencing

        Mechanisms and Applications

        by Tamas Dalmay

        Plant gene silencing is a crucially important phenomenon in gene expression and epigenetics. This book describes the way small RNA is produced and acts to silence genes, its likely origins in defence against viruses, and also its potential to improve plants. Plant gene silencing can be used to improve industrial traits, make plants more nutritious or more valuable to consumers, to remove allergens, and to improve resistance to weeds and pathogens ; Chapter 1: Diversity of RNA silencing pathways in plantsChapter 2: Induction and suppression of silencing by plant virusesChapter 3: Artificial induction and maintenance of epigenetic variations in plantsChapter 4: Gene Silencing in Archaeplastida AlgaeChapter 5: Gene silencing in fungi: A diversity of pathways and functionsChapter 6: Artificial small RNA-based strategies for effective and specific gene silencing in plantsChapter 7: Application of RNA silencing in improving plant traits for industrial useChapter 8: Increasing nutritional value by RNA silencingChapter 9: RNA-based control of plant diseases: a case study with Fusarium graminearumChapter 10: Targeting nematode genes by RNA silencingChapter 11: Gene silencing provides efficient protection against viruses

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      • Trusted Partner
        RNAi for Plant Improvement and Protection
        April 2021

        RNAi for Plant Improvement and Protection

        by Bruno Mezzetti, Jeremy Sweet, Lorenzo Burgos

        RNA interference (RNAi) has the potential to make major contributions towards sustainable crop production and protection with minimal environmental impacts compared to other technologies. RNAi is being developed and exploited both within plants (i.e. host-induced gene silencing, HIGS) and/or as topical applications (e.g. spray-induced gene silencing, SIGS) for targeting pest and pathogen genes and for manipulating endogenous gene expression in plants. Chapters by international experts review current knowledge on RNAi, methods for developing RNAi systems in GM plants and applications for crop improvement, crop production and crop protection. Chapters examine both endogenous systems in GM plants and exogenous systems where interfering RNAs are applied to target plants, pests and pathogens. The biosafety of these different systems is examined and methods for risk assessment for food, feed and environmental safety are discussed. Finally, aspects of the regulation of technologies exploiting RNAi and the socio-economic impacts of RNAi technologies are discussed. Chapter 1: Introduction to RNAi in Plant Production and Protection. Bruno Mezzetti, Jeremy Sweet and Lorenzo Burgos Chapter 2: Gene silencing to induce pathogen-derived resistance in plants. Zhen Liao, Elena Zuriaga, Ángela Polo and Maria L. Badenes Chapter 3: Exogenous application of small RNAs as a tool for gene function discovering. Barbara Molesini and Tiziana Pandolfini Chapter 4: The “Trojan Horse” approach for successful RNA interference in inscects. Dimitrios Kontogiannatos, Anna Kolliopoulou and Luc Swevers. Chapter 5: Biogenesis and functional RNAi in fruit-trees. Michel Ravelonandro and Pascal Briard Chapter 6: Gene silencing or gene editing: the pros and cons. Huw D Jones Chapter 7: Application of RNAi technology in Forest Trees. Matthias Fladung, Hely Haggman and S. Sutela Chapter 8: Host-induced gene silencing and spray-induced gene silencing for crop protection against viruses. Angela Ricci, Silvia Sabbadini, Laura Miozzi, Bruno Mezzetti and Emanuela Noris. Chapter 9: Small talk and large impact: the importance of small RNA molecules in the fight of plant diseases. Kristian Persson Hodén and Christina Dixelius Chapter 10: dsRNA stability during external applications – an overview. Ivelin Pantchev, Goritsa Rakleova and Atanas Atanassov Chapter 11: Boosting dsRNA delivery in plant and insect cells with peptide- and polymer-based carriers: cases-based current status and future perspectives. Kristof de Schutter, Olivier Christiaens, Clauvis Nji Tizi Taning and Guy Smagghe Chapter 12: Environmental safety assessment of RNAi plants for pest control. Salvatore Arpaia, Olivier Christiaens, Paul Henning Krogh, Kimberly Parker and Jeremy Sweet Chapter 13: Food and feed safety assessment of RNAi plants and products. Hanspeter Naegeli, Gijs Kleter and Antje Dietz-Pfeilstetter Chapter 14: Regulatory aspects of RNAi in plant production. Werner Schenkel and Achim Gathmann Chapter 15: The Economics of RNAi technology in plant breeding: from the innovation landscape to consumer acceptance. Dario Frisio and Vera Ventura Chapter 16: Communication challenges of RNAi and selected communication messages from iPLANTA for dissemination. Hilde-Gunn Opsahl-Sorteberg

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      • Trusted Partner
        Gene-for-Gene Relationship in Plant-Parasite Interactions
        Biotechnology
        April 1997

        Gene-for-Gene Relationship in Plant-Parasite Interactions

        by Edited by Ian R Crute, Eric B Holub, Jeremy J Burdon

        Genetics has transformed plant pathology on two occasions: first when Mendelian genetics enabled the discovery that disease resistance was a heritable trait in plants, and secondly when Flor proposed the “gene-for-gene” hypothesis to explain his observations of plant-parasite interactions, based on his work on flax rust in North Dakota starting in the 1930s. Our knowledge of the genetics of disease resistance and host-pathogen coevolution is now entering a new phase as a result of the cloning of the first resistance genes. This book provides a broad review of recent developments in this important and expanding subject. Both agricultural and natural host-pathogen situations are addressed. While most of the book focuses on plant pathology, in the usual sense of the term embracing fungal, bacterial and viral pathogens, there is also consideration of parasitic plants and a chapter demonstrating lessons to be learnt from the mammalian immune system. Three overall themes are addressed: genetic analyses and utilization of resistance; population genetics; and cell biology and molecular genetics. Chapters are based on papers presented at the British Society for Plant Pathology Presidential meeting held in December 1995, but all have been revised and updated to mid-1996. Written by leading authorities from North America, Europe and Australia, the book represents an essential update for workers in plant genetics, breeding, biotechnology and pathology.

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      • Trusted Partner
        Inducible Gene Expression in Plants
        Biotechnology
        March 1999

        Inducible Gene Expression in Plants

        by Edited by Paul H S Reynolds

        The use of inducible gene expression systems is a rapidly developing area of plant molecular biological research. There is considerable interest in the use of these systems as research tools, not only because they allow expression of genes which may be, for example, developmentally lethal, but also because they allow for controlled experiments to be performed in a true isogenic background. They also have the potential to provide a means by which desired characters are expressed in field-based systems in the future.

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      • Trusted Partner
        Die Pyramide
        January 2018

        Die Pyramide

        by Kadare, Ismail / Albanisch Röhm, Joachim

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      • Trusted Partner
        Die rote Pyramide
        February 2022

        Die rote Pyramide

        Erzählungen

        by Sorokin, Vladimir / Übersetzer Tretner, Andreas & Trottenberg, Dorothea

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      • Trusted Partner
        Das Bild der Pyramide
        March 2022

        Das Bild der Pyramide

        Commissario Mont

        by Andrea Camilleri

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      • Trusted Partner
        Verschollen in der Pyramide
        September 2005

        Verschollen in der Pyramide

        by Naumann, Rosa

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      • Trusted Partner
        Genetic Epidemiology
        Epidemiology & medical statistics
        June 2013

        Genetic Epidemiology

        Methods and Applications

        by Melissa A Austin, Terri H Beaty, W David Dotson, Kelly Edwards, Stephanie M Fullerton, Marta Gwinn, Muin J Khoury, Barbara McKnight, Deborah Nickerson, Ruth Ottman, Bruce M Psaty, Stephen M Schwartz, John A Stamatoyannopolous, Janet L Stanford, Timothy A Thornton

        Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described. Concluding with a review of ethical issues and a framework for translating human genomics research to clinical practice and public health benefit, this textbook is an essential new resource for graduate students in epidemiology and public health genetics.

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      • Trusted Partner
        The report of mountain patrol · gene editor baby: clown and history

        The report of mountain patrol · gene editor baby: clown and history

        by Wang Liming

        It's a grand scientific writing plan of Professor Wang Liming. He plans to spend 30 years continuously observing and analyzing the progress and major events of life science in the world, and finishing the book year by year. Gene editor baby: clowns and history is the * edition of this series. Professor Wang Liming combed the 26 life science events that may affect the whole human beings in this year, focusing on 8 of them. He uses a professional eye to dispel the fog and restore the truth of events, so that readers can understand the scientific logic from these vivid events, and understand where human life science exploration has reached and where it will go.

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      • Trusted Partner
        Die Peter-Pyramide
        1987

        Die Peter-Pyramide

        EBGO: die Einheitlich Bürokratische GrundOrdnung

        by Peter, Laurence J / Illustriert von Wuerker, Matt; Englisch Kober, Hainer

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      • Trusted Partner
        Die Peter-Pyramide
        1990

        Die Peter-Pyramide

        EBGO: Die Einheitlich Bürokratische Grundordnung

        by Peter, Laurence J

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      • Trusted Partner
        Der Fluch der Käsops-Pyramide
        February 2013

        Der Fluch der Käsops-Pyramide

        by Stilton, Geronimo / Deutsch Jung, Carsten

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      • Trusted Partner
        The Quest to Conserve Rare Breeds
        Technology, Engineering & Agriculture
        August 2020

        The Quest to Conserve Rare Breeds

        Setting the Record Straight

        by Lawrence Alderson

        Since the middle of the twentieth century the world has witnessed a succession of political and social disruptions. Globalisation, technological advancement, climate change, human migration, war and conflict - all have caused major worldwide upheavals. In this light, it's unsurprising that conservation of rare breed animals has been neglected. Yet the preservation of these genetic resources - this biological diversity - is an essential ingredient of sustainable life on Earth, and not something we can afford to lose. This book, straight from the 'horse's mouth' Lawrence Alderson CBE, challenges often repeated 'facts' about livestock farming and argues for a reasoned and evidence-based approach from political and public circles. Correcting misconceptions as he goes, he recounts the creation and development of the rare breed conservation movement, addresses extinctions and genetic safe-guarding measures, and considers where we go from here. Challenged as we are by climate change, sustainability and feeding the world, perhaps it is these endangered animals that hold the answer - perhaps with them, we can adapt to our changing environment and see a way forward to a more certain future.

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      • Trusted Partner
        How to understand a new disease
        January 2021

        How to understand a new disease

        Patrol report

        by Wang Liming

        This book sorts out major events in life sciences from November 2019 to October 2020. In the first part, the author focuses on the progress made by scientists, especially Chinese scientists, in the context of the new crown epidemic. Including how to discover the new coronavirus, treat new coronary pneumonia, vaccine research and other issues that readers are concerned about. In the second part, the author combed the progress in the field of life sciences in 2020, including cutting-edge scientific researches such as organ transplantation, Alzheimer's disease, and gene editing. This book is recommended by Han Qide and He Fan in a preface. It is suitable for party and government agencies, practitioners in the pharmaceutical industry, and readers who care about life sciences.

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