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      • Fast Facts: Bleeding Disorders
        Haematology
        February 2013

        Fast Facts: Bleeding Disorders

        by David Green, Christopher A Ludlam

        Most hemorrhagic problems are emergencies, requiring rapid diagnosis and prompt management to stop bleeding. In some cases, such as nose bleeds, large bruises and heavy menses, it is the clinician’s responsibility to discern whether the patient has a clinically significant bleeding disorder that may predispose to excessive or potentially serious bleeding. Fast Facts: Bleeding Disorders keeps a complex subject simple and clinically oriented. The authors have made numerous updates to this second edition to ensure it provides essential information in a readily accessible format. Fast Facts: Bleeding Disorders remains a comprehensive up-to-date reference that reflects the latest research and clinical guidelines. It will assist primary care providers, physician assistants, nurse-clinicians, pharmacists, residents and doctors in training as they confront the challenges of controlling bleeding in patients with hemophilia, von Willebrand disease, platelet disorders and thrombosis, or as a result of antithrombotic or anticoagulant therapy. It is a small book packed with important information, designed to swiftly improve patient treatment and outcomes.

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      • Advances in the Treatment of B-Cell Chronic Lymphocytic Leukemia
        Medicine
        March 2012

        Advances in the Treatment of B-Cell Chronic Lymphocytic Leukemia

        by Michael J Keating, Constantine Tam

        The past two decades have seen substantial advances in the understanding of chronic lymphocytic leukemia (CLL), including new insights from genetics and molecular biology regarding the heterogeneity in clinical behavior observed in this disease. The Editors highlight how vast and complex the CLL has become, but foresee a new dawn for physicians and researchers seeking to better understand and treat the disease. In reflecting on these advances, the eight chapters of this book from international experts address key issues in understanding CLL, its current management and future prospects for treatment. Topics include diagnosis & staging, genetics of disease, treatment options and chemotherapy, stem cell transplantation, options in refractory disease, prognostic factors and future directions for management.

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      • Current & Emerging Options for Hereditary Angioedema Management
        Haematology
        August 2012

        Current & Emerging Options for Hereditary Angioedema Management

        by Marco Cicardi

        Hereditary angioedema is a rare but severely disabling and life-threatening disease with an estimated prevalence in the general population of 1:50,000. However, the cardinal symptom – recurrent cutaneous swellings – can develop in many common conditions such as allergic reaction to food and drugs. This book reviews in detail the therapeutic options that are available for hereditary angioedema, and provides physicians with the necessary knowledge to give their patients the appropriate treatments.

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      • Non-Hodgkin Lymphomas: Advanced Diagnostics and Personalized Therapies
        Haematology
        June 2013

        Non-Hodgkin Lymphomas: Advanced Diagnostics and Personalized Therapies

        by Antonino Carbone, Anas Younes

        This book presents the most recent developments in the areas of advanced diagnostics and treatment of lymphoma. Success in matching patients with effective and safe novel targeted therapy depends on standardized acquisition and analysis of biological samples. This multidisciplinary work of 20 chapters from renowned leaders demonstrates how integration between medical skills, scientific knowledge and professional proficiency is becoming increasingly critical for successful implementation of personalized healthcare.

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      • Advances in the Treatment of Chronic Myeloid Leukemia
        Haematology
        July 2013

        Advances in the Treatment of Chronic Myeloid Leukemia

        by Giuseppe Saglio, Carmen Fava

        The discovery of the pathogenetic role of BCR-ABL and the advent of tyrosine kinase inhibitors has revolutionized the prognosis for Philadelphia-positive chronic myeloid leukemia (CML). Nevertheless, many challenges remain. In eight concise chapters, this book provides an expert overview of the state-of-the-art in addressing CML. Coverage includes diagnosis, risk classification, disease genetics, molecular monitoring, treatment options, prognostic factors and future prospects for disease management and the possibility of cure.

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      • Novel Insights into Pathophysiology, Diagnostics and Treatment of Myelodysplastic Syndromes
        Haematology
        January 2014

        Novel Insights into Pathophysiology, Diagnostics and Treatment of Myelodysplastic Syndromes

        by Rainer Haas, Ulrich Germing

        Myelodysplastic syndromes (MDS) belong to the most frequent malignant diseases of the bone marrow, especially in the elderly. Diagnosis and prognostication in MDS often is not easy. Treatment decision-making is often hampered by the lack of beneficial compounds but also by the lack of understanding the pathophysiology of the diseases. This book, dedicated to MDS, aims to present, summarize and discuss the pathophysiological concept, diagnostic procedures and therapeutic approaches.

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      • Contemporary Approaches to Hemophilia
        Haematology
        February 2014

        Contemporary Approaches to Hemophilia

        by Erik Berntorp

        Hemophilia is an age-old disease, but the distinction between hemophilia A and B was not made until the 1940s and 1950s. At that time, it was a disease with a very poor prognosis with an expected median survival of little more than 10 years. Since then, evolution of the understanding of the disease and treatment has been explosive. In this book, hemophilia is addressed from both a basic science and a practical perspective. The eight chapters are written by some of the most distinguished hemophilia experts in the world, sometimes in collaboration with members of the next generation of professionals. The content is up to date, reliable and written in a manner that will engage and educate less-experienced staff at hemophilia treatment centers and hematology departments to promote the development of care in hemophilia. The book will also interest professionals from related disciplines, together with students and administrators.

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      • Current Approach to Hyperammonemia
        Haematology
        March 2015

        Current Approach to Hyperammonemia

        by Johannes Häberle

        Hyperammonemia is a metabolic condition characterized by increased concentrations of ammonia in the blood. Due to the neurotoxic effects of ammonia, a nitrogenous compound, it is a highly dangerous condition, particularly during infantile and early childhood development. Ammonia-induced damage to the brain may fast become irreversible depending on the duration and extent of hyperammonemia. Despite this, the mechanisms by which brain function is severely hampered or irreversibly destroyed have not yet been fully elucidated. This book brings together basic scientists and researchers, as well as clinicians caring for pediatric or adult patients, in an effort to shed light on the various biochemical, analytical and clinical aspects of hyperammonemia; it covers current approaches and the latest advances in state-of-the-art management, as well as providing future perspectives on the condition.

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      • Current & Emerging Treatments for Immune Thrombocytopenia
        Haematology
        February 2013

        Current & Emerging Treatments for Immune Thrombocytopenia

        by Abdulgabar Salama

        Immune thrombocytopenia (ITP) is the best characterized human autoimmune disease and affects approximately 5% of the world’s population. Clinically, it is defined by a low platelet count and increased bleeding risk. In this book, international experts provide a rounded overview of the disease and its management. The pathogenesis of this multifactorial and heterogeneous disease is addressed in the opening chapter. Following a chapter on symptoms and diagnosis, there is an overview of treatment options and an algorithm for therapy. Subsequent chapters review the various medical approaches available, including steroids, immunoglobulins, immunosuppressants, TPO receptor agonists, and other interventions such as platelet transfusion and surgical approaches.

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      • Current & Emerging Therapeutics for Multiple Myeloma
        Haematology
        September 2013

        Current & Emerging Therapeutics for Multiple Myeloma

        by Noopur Raje, Sundar Jagannath

        The evolution of therapies for the treatment of multiple myeloma and related plasma cell dyscrasias has succeeded in transforming myeloma into a chronic disease. Conventional chemotherapy has been widely superseded by novel more targeted approaches impacting both the tumor cell and the microenvironment in which it resides. The seven chapters of this book highlight these advances and tackle the current landscape of therapies available to patients. The role of stem cell transplantation in the era of these novel agents is discussed, together with novel approaches under evaluation in early phase trials. This book provides a succinct overview of the evolving treatment paradigm of therapies in myeloma and will provide the reader with the context for use of such therapies.

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      • Fast Facts: Lymphoma
        Haematology
        January 2008

        Fast Facts: Lymphoma

        by Chris Hatton, Graham Collins, John Sweetenham

        Lymphomas arise from a single abnormal lymphocyte, yet many different subtypes of lymphoma occur. Recent advances in cellular and molecular techniques have revolutionized physicians' understanding of this malignancy, and there have been dramatic developments in diagnosis and treatment.Fast Facts: Lymphoma gives a comprehensive and up-to-date perspective on this challenging disease written by three experts in the field. Starting with a clear outline of the nature of lymphoma, its diagnosis, staging and management, this concise handbook goes on to provide specific details of individual lymphoma entities and treatment modalities.Fast Facts: Lymphoma is a valuable handbook for training doctors and specialist nurses working in the field of hemato-oncology, and will be of interest to the inquiring patient or carer who wishes to know more about lymphoma. Table of contents: Epidemiology Cellular and molecular aspects Diagnostic and laboratory techniques General approach to management Aggressive B-cell high-grade lymphomas Indolent B-cell lymphomas Immunocompromised and HIV-positive patients Hodgkin lymphoma Treatment modalities Supportive care

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      • Fast Facts: Lymphoma
        Medicine
        July 2014

        Fast Facts: Lymphoma

        by Chris Hatton, Graham Collins, John Sweetenham

        Lymphomas arise from a single abnormal lymphocyte, yet many different subtypes of lymphoma occur. Recent advances in cellular and molecular techniques have revolutionized physicians' understanding of this malignancy, and there have been dramatic developments in diagnosis and treatment. Fast Facts: Lymphoma gives a comprehensive and up-to-date perspective on this challenging disease written by three experts in the field. Starting with a clear outline of the nature of lymphoma, its diagnosis, staging and management, this concise handbook goes on to provide specific details of individual lymphoma entities and treatment modalities. Fast Facts: Lymphoma is a valuable handbook for training doctors and specialist nurses working in the field of hemato-oncology, and will be of interest to the inquiring patient or carer who wishes to know more about lymphoma.

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      • Fast Facts: Lymphoma
        Medicine
        October 2014

        Fast Facts: Lymphoma

        by Chris Hatton, Graham Collins, John Sweetenham

        Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. Fast Facts: Lymphoma distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma. Written by three experts in the field from the UK and USA, Fast Facts: Lymphoma applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma.

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      • Fast Facts: Lymphoma
        Medicine
        October 2014

        Fast Facts: Lymphoma

        by Chris Hatton, Graham Collins, John Sweetenham

        Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. Fast Facts: Lymphoma distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma. Written by three experts in the field from the UK and USA, Fast Facts: Lymphoma applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma.

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      • Fast Facts: Myeloma for Patients and their Supporters
        Medicine
        November 2016

        Fast Facts: Myeloma for Patients and their Supporters

        by Karthik Ramasamy

        Kicking off with Fast Facts: Myeloma for Patients and Supporters, these invitingly short, highly illustrated workbooks (FastTests included!) aim to fill the gap when you’re wondering ‘what’s best to recommend to my patients?’. Information + Taking Control = Best Outcome is the theme running through our new series, the first reviews for which speak for themselves (see below).

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      • Fast Facts: Lymphoma
        Medicine
        October 2014

        Fast Facts: Lymphoma

        by Chris Hatton, Graham Collins, John Sweetenham

        Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. Fast Facts: Lymphoma distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma. Written by three experts in the field from the UK and USA, Fast Facts: Lymphoma applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma.

        More
      • Fast Facts: Myeloma for Patients and their Supporters
        Medicine
        November 2016

        Fast Facts: Myeloma for Patients and their Supporters

        by Karthik Ramasamy

        Kicking off with Fast Facts: Myeloma for Patients and Supporters, these invitingly short, highly illustrated workbooks (FastTests included!) aim to fill the gap when you’re wondering ‘what’s best to recommend to my patients?’. Information + Taking Control = Best Outcome is the theme running through our new series, the first reviews for which speak for themselves (see below).

        More
      • Fast Facts: Cutaneous T-cell Lymphoma
        Medicine
        April 2019

        Fast Facts: Cutaneous T-cell Lymphoma

        by Haun, Paul L., Scarisbrick, Julia J.

        Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient. ' Fast Facts: Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists, and oncologists to communicate effectively with pathologists in the diagnosis of this chronic condition, aided by over 100 superb clinical and pathological images, and to provide tailored long-term care for their patients. This concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology, immunophenotyping and treatment of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is essential reading for pathologists, non-specialist clinicians and dermatology and oncology trainees.

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      • Fast Facts: Cutaneous T-cell Lymphoma
        Medicine
        April 2019

        Fast Facts: Cutaneous T-cell Lymphoma

        by Haun, Paul L., Scarisbrick, Julia J.

        Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient. ' Fast Facts: Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists, and oncologists to communicate effectively with pathologists in the diagnosis of this chronic condition, aided by over 100 superb clinical and pathological images, and to provide tailored long-term care for their patients. This concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology, immunophenotyping and treatment of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is essential reading for pathologists, non-specialist clinicians and dermatology and oncology trainees.

        More

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