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Genome editing offers a powerful tool to significantly accelerate crop-breeding programs in order to develop new and improved varieties. It allows precise modification of an organism's DNA sequence, often by creating targeted double-strand breaks at specific locations. The CRISPR-Cas system has emerged as the preferred method of gene editing and offers a powerful technology for crop improvement. The use of CRISPR in plant research has led to significant improvements in crop performance in terms of yield, nutrition, stress tolerance and resistance against agricultural pests and diseases. This book explores the cutting-edge field of genome editing, its applications and potential to revolutionize the genetic improvement of crops. It includes: Foundational concepts and historical context of genome editing (GE). Structure and mechanisms of various genome editing techniques. Application of GE for trait improvements in plants. Regulatory, biosafety, and ethical considerations. This is a valuable resource for researchers in crop genetic improvement, graduate and postgraduate students in molecular biology and biotechnology programs, and professionals in the field.
Gene expression in cells follows a prescribed pathway that conforms to the Central Dogma; where the genetic information stored in DNA is transcribed into RNA and then expressed into proteins, which influences most plant traits. Plant salt tolerance research is directed towards identifying nucleotide variants that could contribute to tolerant phenotypes. This book comprehensively presents the current state of knowledge on plant salt tolerance through meticulous analysis of the processes operating across the Central Dogma. It provides a detailed account of modulation of gene expression through genome editing systems to achieve crop improvement against salt stress. It also provides state-of-the-art information on advances in breeding technologies of genome selection and accelerated de novo domestication for rapidly improving the salt tolerance of plants for global food security. This book: 1.Provides a comprehensive coverage of plant salt tolerance mechanisms. 2.Spotlights various factors functioning along the Central Dogma pathway and their regulation in response to salinity. 3.Examines how these factors function to protect the plants from high salinity. 4.Highlights advances in cutting-edge breeding technologies for improving salt tolerance. The book will be of particular value to students and researchers of plant genetics, molecular biology and physiology and those with an interest in salinity and salt tolerance.
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Technology for modifying the genotypes and phenotypes of insects and other arthropods has steadily progressed by development of more precise and powerful methods, most prominently transgenic modification. There is now almost unlimited ability to modify phenotypes to benefit human health and agriculture. Precise DNA modifications and gene drive particularly have the power to make wild-type populations less harmful in ways that could never be performed with previous transgenic approaches. This transition from primarily laboratory science to greater prominence for field applications has also necessitated a greater development of modelling, ethical considerations and regulatory oversight. The 2nd edition of Transgenic Insects contains chapters contributed by experts in the field that cover the technology and applications that are now possible. These include an increased emphasis on acceptance issues that will be necessary for application of many technologies.
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The rapid progress in molecular genetic techniques and molecular biology has led to a great expansion in the range of biotechnology applications in agriculture. The field is supported by a large number of basic and applied sciences, and agricultural biotechnology has become a multidisciplinary field. A vast amount of technical terms is required to be grasped by students, teachers and research workers and this new Glossary of Agricultural Biotechnology covers all the scientific areas in this important field, including agricultural biotechnology, artificial intelligence, bioinformatics, biostatistics, cell biology, computer science, CRISPR/Cas, cytogenetics, DNA nanotechnology, epigenetics, epigenomics, genetics, genome editing, genomics, intellectual property rights, molecular biology, molecular genetics, nanobiotechnology, plant breeding, plant pathology, plant physiology, remote sensing, therapeutics, and tissue culture. The book includes: · Common abbreviations in agricultural biotechnology · Brief descriptions and definitions of each term written in a user-friendly style · A comprehensive bibliography. This book is designed to be an easy-to-use reference for students, teachers, research workers, workers in biotechnology-related government agencies, and the biotechnology industry.
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Methods in microbial systematics have developed and changed significantly in the last 40 years. This has resulted in considerable change in both the defining microbial species and the methods required to make reliable identifications. Developments in information technology have enabled ready access to vast amounts of new and historic data online. Establishing both the relevance, and the most appropriate use, of this data is now a major consideration when undertaking identifications and systematic research. This book provides some insights into how current methods and resources are being used in microbial systematics, together with some thoughts and suggestions as to how both methodologies and concepts may develop in the future. It includes coverage of: The philosophy and changes in microbial systematics, including the relevance of names, new concepts of species, and the issues encountered with species that cannot be grown in culture. The application of new identification technologies, specifically those based on nucleic acids and complex chemo-taxonomic methods. The challenges of using published databases and other data resources in arriving at an identification appropriate to current species concepts. The practical requirements of an identification: obtaining and verifying reference cultures and data, and the type and level of identification required by different users. This book is suitable for academic researchers, scientists involved with identification or survey, microbiologists, students and extension workers.
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Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals. Topics covered include structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, evolution of DNA sequences, comparative chromosome mapping and painting, genome databases, gene prediction and the use of genomic information to understand inherited diseases. Contributors include leading researchers from Europe, USA, Australia and Japan.
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This book summarises the impacts that the genome sequencing revolution has had in all areas across animal and plant agriculture, including cattle, orphan crops, cash crops, and more, with reference to applications in many species and locations. It explains new techniques and their use in understanding epigenetics, breeding and conservation.
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Quantifying Diets of Wildlife and Fish presents different techniques available to study animal diets. Ecologists determine animal diets to build natural history knowledge, test hypotheses in ecological theory and make informed management decisions for important ecosystems. Many researchers use techniques traditionally applied to the animals they study, rather than choose from the techniques with greatest potential for their study. In an effort to encourage researchers to consider new approaches, this book focuses on the techniques, rather than on particular groups of organisms or specific environments. With contributions from leading ecologists, chapters explore experimental design, observational techniques (including new technologies), stomach contents and faecal analysis, eDNA, tracers and stable isotopes. They also cover the latest multivariate methods of analyses suitable for describing animal diets and feeding relationships, as well as testing hypotheses relevant to ecological theory, environmental management and biological conservation. The expert knowledge provided will encourage readers to look beyond the boundaries of their specialties, assist in testing important hypotheses and provide insights into management problems. The examples in this book cover a range of vertebrates and invertebrates, as well as different environments, to open these methods up for novice ecologists and stimulate lateral thinking in more experienced researchers.
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Conventional plant breeding alone can no longer sustain the rising global demand for food. Genetic engineering technology makes it possible to develop new crop varieties with improved yield performance, specific quality attributes (external and internal in vegetable crops), resistance to diseases and insect pests, and environmental stresses. Genetic engineering technology for developing GM crops is complementary to genome editing and other breeding technologies. In addition to food requirements, transgenic crops have the possibility to carry edible vaccines and therapeutic proteins, to help combat human disease and malnutrition. This book reviews the importance and safety of transgenic vegetable crops and covers a wide variety of crops and different technologies. It includes: Genetic engineering in tomato, eggplant, peppers, amaranth, cauliflower, carrot, cucurbits, potato, tropical tubers and melons. Transgenic resistance to viral diseases. Embryogenic cell suspension culture. Genome editing and CRISPR/Cas9. Molecular techniques for biofortification. RNAi strategies for vegetable crop improvement. Designing futuristic vegetable crop varieties. This book is suitable for researchers in horticulture, plant science, and agricultural biotechnology as well as practitioners in vegetable breeding and seed production.
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Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described. Concluding with a review of ethical issues and a framework for translating human genomics research to clinical practice and public health benefit, this textbook is an essential new resource for graduate students in epidemiology and public health genetics.
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This book integrates a science and business approach to provide an introduction and an insider view of intellectual property issues within the biotech industry, with case studies and examples from developing economy markets. Broad in scope, this book covers key principles in pharmaceutical, industrial, and agricultural biotechnology within four parts.Part 1 details the principles of intellectual property and biotechnology. Part 2 covers plant biotechnology, including biotic and abiotic stress tolerance, GM foods in sustainable agriculture, microbial biodiversity and bioprospecting for improving crop health and productivity, and production and regulatory requirements of biopesticides and biofertilizers. The third part describes recent advances in industrial biotechnology, such as DNA patenting, and commercial viability of the CRISPR/Cas9 system in genome editing. The final part describes intellectual property issues in drug discovery and development of personalized medicine, and vaccines in biodefence.This book is an ideal resource for all postgraduates and researchers working in any branch of biotechnology that requires an overview of the recent developments of intellectual property frameworks in the biotech sector.
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Since the publication of Plant Genotyping: the DNA Fingerprinting of Plants in 2001, the techniques available for plant DNA analysis have advanced considerably. Recent developments focus on high throughput methods, and generally target single nucleotide polymorphism (SNP) discovery and analysis. SNPs represent the most common form of genetic variation in both plants and animals, and play a key role in revealing the molecular mechanisms underlying traits. Plant Genotyping II: SNP Technology describes some of the import recent developments in this field, with the main focus on SNPs. Contributions cover the discovery, analysis and uses of SNPs, while also examining other approaches to plant genotyping.
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Praise for the previous edition: "Honor Book" (Science Grades 7-12 category)—Society of School Librarians International Blood, Bugs, and Plants, Revised Edition explores several core biological areas that have influenced modern forensic science. Entomology ("bugs") is a specialty that uses knowledge about insect life cycles to inform death investigations. Botany ("plants") is a specialty that looks at plant materials as evidence in cases. Occupying the largest part of this eBook, the "blood" section covers the identification of blood and body fluids (determining their origin as human or animal), DNA typing, and blood-spatter patterns. Blood, Bugs, and Plants, Revised Edition takes a look at an exciting area of forensic science. Each chapter in this fascinating eBook provides an overview that briefly introduces readers to basic concepts in forensic science, allowing them to understand how this biological science sheds light on issues in legal cases. The forensic science specialty of criminalistics is also discussed in this comprehensive resource. Chapters include: History and Pioneers Scientific Principles: DNA and Genetics Forensic Analysis: Evaluation and Identification Testing of Blood and Body Fluid Evidence Forensic Analysis: DNA Typing Forensic Analysis: Bugs and Plants The Future.
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Romantische LennleaMomente garantiert: Alea und Lennox reisen über Land zum sagenumwobenen LoreleyFelsen, wo sie Aleas Zwillingsschwester Anthea vermuten. Mithilfe von Nelanis Rückverwandler und Antheas DNA wollen sie dort Aleas Meermädchenfähigkeiten reaktivieren. Wird das Experiment gelingen?
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This guide provides patients with important medical information about interactions of their drug products with vitamins and minerals. These interactions are not always listed in the accompanying package inserts. Those who take acid blockers such as omeprazole or pantoprazole may not only develop disorders relating to calcium, magnesium, vitamin D and bone metabolism in the long term, but above all become deficient in vitamin B12. This way, patients can improve their treatment, reduce the side effects of their medication and increase their quality of life!
