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      • Trusted Partner
        Science & Mathematics
        April 2021

        Medicalising borders

        Selection, containment and quarantine since 1800

        by Sevasti Trubeta, Christian Promitzer, Paul Weindling, Hastings Donnan

        The research of pandemics, epidemics, and pathogens like COVID-19 reaches far beyond the scope of biomedicine. It is not only an objective for the health, political and social sciences, but epidemics and pandemics are a matter of geography: foci and vectors of communicable diseases continue to test the efficacy of medical control at state borders. This volume illuminates these issues from various disciplinary viewpoints. It starts by exploring historical models of quarantine, spatial isolation and detention as precautionary means against the dissemination of disease and contagion by border crossers, migrants and refugees. Besides the patterns of prejudice with which these groups are confronted, the book also deals with various kinds of fear of contamination from outside of the nation state. The contributors address the implementation of medical techniques at state borders in the twentieth and early twenty-first centuries, as well as the presently practiced measures of medical and biometric screening of migrants and refugees. Uniquely, this volume shows that the current border security regimes of Western states exhibit a high share of medicalised techniques of power, which originate both in European modernity and in the medical and biological disciplines developed during the last quarter of the millennium. Drawing on the collective expertise of a network of international researchers, this interdisciplinary volume is essential reading for those wishing to understand the medicalisation of borders across the globe, from the early eighteenth century up to the present day.

      • Computer security
        February 2006

        Summary of a Workshop on the Technology, Policy, and Cultural Dimensions of Biometric Systems

        by Kristen Batch, Lynette I. Millett, Joseph N. Pato, Editors, Whither Biometrics Committee, National Research Council

        Biometricsâ€"the use of physiological and behavioral characteristics for identification purposesâ€"has been promoted as a way to enhance security and identification efficiency. There are questions, however, about, among other issues, the effectiveness of biometric security measures, usability, and the social impacts of biometric technologies. To address these and other important questions, the NRC was asked by DARPA, the DHS, and the CIA to undertake a comprehensive assessment of biometrics that examines current capabilities, future possibilities, and the role of the government in their developments. As a first step, a workshop was held at which a variety of views about biometric technologies and systems were presented. This report presents a summary of the workshop’s five panels: scientific and technical challenges; measurement, statistics, testing, and evaluation; legislative, policy, human, and cultural factors; scenarios and applications; and technical and policy aspects of information sharing. The results of this workshop coupled with other information will form the basis of the study’s final report.

      • Computer security
        December 2010

        Biometric Recognition

        Challenges and Opportunities

        by Joseph N. Pato and Lynette I. Millett, Editors; Whither Biometrics Committee; Computer Science and Telecommunications Board; Division on Engineering and Physical Sciences; National Research Council

        Biometric recognition--the automated recognition of individuals based on their behavioral and biological characteristic--is promoted as a way to help identify terrorists, provide better control of access to physical facilities and financial accounts, and increase the efficiency of access to services and their utilization. Biometric recognition has been applied to identification of criminals, patient tracking in medical informatics, and the personalization of social services, among other things. In spite of substantial effort, however, there remain unresolved questions about the effectiveness and management of systems for biometric recognition, as well as the appropriateness and societal impact of their use. Moreover, the general public has been exposed to biometrics largely as high-technology gadgets in spy thrillers or as fear-instilling instruments of state or corporate surveillance in speculative fiction. Now, as biometric technologies appear poised for broader use, increased concerns about national security and the tracking of individuals as they cross borders have caused passports, visas, and border-crossing records to be linked to biometric data. A focus on fighting insurgencies and terrorism has led to the military deployment of biometric tools to enable recognition of individuals as friend or foe. Commercially, finger-imaging sensors, whose cost and physical size have been reduced, now appear on many laptop personal computers, handheld devices, mobile phones, and other consumer devices. Biometric Recognition: Challenges and Opportunities addresses the issues surrounding broader implementation of this technology, making two main points: first, biometric recognition systems are incredibly complex, and need to be addressed as such. Second, biometric recognition is an inherently probabilistic endeavor. Consequently, even when the technology and the system in which it is embedded are behaving as designed, there is inevitable uncertainty and risk of error. This book elaborates on these themes in detail to provide policy makers, developers, and researchers a comprehensive assessment of biometric recognition that examines current capabilities, future possibilities, and the role of government in technology and system development.

      • Agriculture & farming
        August 2014

        Biostatistics

        Basic Concepts and Methodology

        by K.S.Kushwaha & C.M.Pandey

        The book is aimed at providing an understanding of basic principles and practices of Biostatistics. Attempt has been made to give a comprehensive inside into the basic concepts of biostatistics i.e. sound easy to read, relevant and useful to students and practitioners of biostatistics. The book includes the design of clinical trials and epidemiological studies collection of data, research methods, clinical measurement and sample size, calculations for various study designs. This makes it a handbook of biostatistics for students and researchers for agriculture, veterinary, life sciences, medicine, public health, biological and social sciences.

      • Methods in Biostatistics, 4/Ed.

        by NEGI

        The 3rd Edition of Methods in Biostatistics has been introduced with some inclusions of important parts of the subject concerned. The latest text which is in your hands is valuable to undergraduate and postgraduate students.  It is also useful to para medical students, nursing students and other health professionals. There are several features that distinguish this book from other textbooks in the field of Biostatistics. The present edition is written lucidly on the unknown to known format with more emphasis given on the logical presentation of the subject-matter by illustrating many more examples and exercises, i.e. problem-based learning methodology. For quick summarization of important and conceptualized words, glossary and list of essential formulae are included. Thus, glossary is an extension and additive support to the learning material (book).

      • October 2014

        Plant Taxonomy and Biosystematics

        Classical and Modern Methods

        by T.S.Rana, K.N.Nair & D.K.Upreti

        The basic aim of this manual is to provide useful resource materials for training young students and faculties working in the area of plant systematics. The manual provides updated information on basic as well as applied aspects of plant systematics on various groups of plants like Algae, Lichens, Bryophytes, Pteridophytes, Gymnosperms and Angiosperms. 1 to 3 describe the various approaches and methods to study microbial and fungal diversity, which is basically a very useful precursor to the students and young researchers. 4 and 5 provide deals with the multi-dimensional approaches in Lichen systematics. The book progresses upwards through the plethora of information on the diversity and systematics of Algae, Bryophytes, Pteridophytes and Gymnosperms ( 6-10). 11 to 15 contain on the plant methodological details identification, approaches and methods of Flora, revision, monograph and development of herbarium. This information is very important for the students and young faculties who intend to pursue their researches in plant taxonomy. 14 and 15 particularly provide all the relevant information on the International Code of Plant nomenclature including cultivated plants. These s per se are very significant for the amateur as well as serious readers of plant taxonomy. Plant taxonomy and biosystematics is a dynamic subject, as it derives information from various other disciplines like palynology, seed morphology, pharmacognosy, molecular biology, etc. We have, therefore, broaden the scope of this book by including the s on palynology, seed morphology, molecular systematics, biostatistics, ecological and remote sensing methods for diversity analyses, and pharmacognostical tools for identification of herbal drugs ( 16-22). The knowledge and information on these applied aspects of biology in relation to taxonomy will certainly infuse the interest in readers, who are pursuing plant taxonomy as their scientific pursuits. 23 and 24 describe the various methods of characterization and evaluation of ornamental and medicinal plants. The last (25) of the book provides the information about CSIR-NBRI Botanic Garden and its various repositories, which could be of great interest to the readers from the perspectives of plant conservation.

      • Medicine
        October 2005

        Cord Blood

        Establishing a National Hematopoietic Stem Cell Bank Program

        by Committee on Establishing a National Cord Blood Stem Cell Bank Program, Emily Ann Meyer, Kathi Hanna, and Kristine Gebbie, Editors

        With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines: The role of cord blood in stem cell transplantation The current status of blood banks already in existence The optimal structure for the cord blood program The current use and utility of cord blood for stem cell transplants The best way to advance the use of cord blood units and make them available for research Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders.

      • Pharmacology
        January 2011

        Perspectives on Biomarker and Surrogate Endpoint Evaluation

        Discussion Forum Summary

        by Alison Mack, Erin Balogh, and Christine Micheel, Rapporteurs; Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease; Institute of Medicine

        In 2010 the Institute of Medicine (IOM) recommended a framework for the evaluation of biomarkers in the chronic disease setting. Published in the book Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease, the framework is intended to bring consistency and transparency to the previously disparate process of biomarker evaluation. Following the book's release, the IOM convened a 2-day discussion forum in Washington, DC, in order to provide an opportunity for stakeholders to learn about, react to, and discuss the book. Presentations reviewed the authoring committee's work process, recommendations, and provided perspectives on the book from the point of view of participants. Thomas Fleming, professor of biostatistics and statistics at the University of Washington, gave a keynote presentation on the critical issues in the validation of surrogate endpoints, a specific use of a biomarker. The present volume recounts the discussion forum proceedings, focusing in turn on each represented sector. A summary of Dr. Fleming's presentation then sets the committee's recommendations within the context of biomarker utilization. Lastly, this summary examines the main themes raised by stakeholders, and the challenges and opportunities presented to stakeholders by the book's recommendations.

      • Aquaculture & fish-farming: practice & techniques
        January 2008

        Applied Bioinformatics, Statistics and Economics in Fisheries Research

        by Ajit Kumar Roy & Niranjan Sarangi

        The bookis first of its kind available in the market. The book spreading over 42 s within three broad sections like aqua-informatics, statistics and economics has covered the advanced tools and techniques of bioinformatics and statistics for exploratory analysis of genomic and microarray data of fishes.Chapters on the latest developments on biotechnological approaches for fish disease diagnostic, infection and immunity of brood carps, cryoconservation of fishes, probiotics and nanotechnology in aquaculture are of paramount interest, in addition to information on prawn aquaculture, ornamental fish farming and trade. Information on various software and their application for exploratory data analysis and data mining leading to knowledge discovery and visualization is the main attraction of the book. Another important feature of the book is that one can find appropriate as well as illustrated examples exclusively with fisheries data. The statistics section includes biometrical and qualitative techniques in genetics and selective breeding of fish, besides fundamental statistical test, design of experiments and sampling methods for planning of experiments and survey in fisheries and aquaculture research. The book also includes econometric approach for technical efficiency estimation and input-output analysis, project evaluation, and impact assessment, linear programming, market intelligence, fisheries legislation, policy and IPR issues all of which are new in the field of fisheries and aquaculture. The book will not only be beneficial to students, but also will be a helpful guidance to researchers and planners for taking policy decisions as it covers a wide range of subjects that are gainfully applied to the fisheries and aquaculture research

      • Agriculture & farming
        January 2022

        Plant Breeding

        Fundamentals and Applications

        by A.K. Sharma

        Plant breeders employ a variety of techniques to improve the genetic composition of the crop and a successful strategy is dependent on the physical, physiological and hereditary characteristics of the plant.

      • Diseases & disorders
        December 2012

        Monitoring HIV Care in the United States

        A Strategy for Generating National Estimates of HIV Care and Coverage

        by Morgan A. Ford and Carol Mason Spicer, Editors; Committee to Review Data Systems for Monitoring HIV Care; Board on Population Health and Public Health Practice; Institute of Medicine

        In September 2010, the White House Office of National AIDS Policy commissioned an Institute of Medicine (IOM) committee to respond to a two-part statement of task concerning how to monitor care for people with HIV. The IOM convened a committee of 17 members with expertise in HIV clinical care and supportive services, epidemiology, biostatistics, health policy, and other areas to respond to this task. The committee's first report, Monitoring HIV Care in the United States: Indicators and Data Systems, was released in March 2012. The report identified 14 core indicators of clinical HIV care and mental health, substance abuse, and supportive services for use by the Department of Health and Human Services (HHS) to monitor the impact of the National HIV/AIDS Strategy (NHAS) and the Patient Protection and Affordable Care Act (ACA) on improvements in HIV care and identified sources of data to estimate the indicators. The report also addressed a series of questions related to the collection, analysis, and dissemination of data necessary to estimate the indicators. In this second report, Monitoring HIV Care in the United States: A Strategy for Generating National Estimates of HIV Care and Coverage, the committee addresses how to obtain national estimates that characterize the health care of people with HIV within the context of the ACA, both before 2014 and after 2014, when key provisions of the ACA will be implemented. This report focuses on how to monitor the anticipated changes in health care coverage, service utilization, and quality of care for people with HIV within the context of the ACA.

      • Pollution & threats to the environment
        September 2000

        Review of the U.S. Navy Environmental Health Center's Health-Hazard Assessment Process

        by Subcommittee on Toxicological Hazard and Risk Assessment, Committee on Toxicology, Board on Environmental Studies and Toxicology, National Research Council

        A large number of chemicals are used on land at shore facilities, in the air in combat and reconnaissance aircraft, on seas around the world in surface vessels, and in submarine vessels by the navy and marine corps. Although the chemicals used are for the large part harmless, there is a significant amount of chemicals in use that can be health hazards during specific exposure circumstances. The Navy Environmental Health Center (NEHC) is primarily tasked with assessing these hazards. The NEHC completes its tasks by reviewing toxicological and related data and preparing health-hazard assessments (HHAs) for the different chemicals. Since the NEHC is continually asked to develop these HHAs, the National Research Council (NRC) was asked to assess independently the validity and effectiveness of NEHC's HHA process, in order to determine whether the process as implemented provides the Navy with the best, comprehensive, and defensible evaluations of health hazards and to identify any elements that might require improvement. The task was assigned to the Board on Environmental Studies and Toxicology's Committee on Toxicology's (COT's) Subcommittee on Toxicological hazard and Risk Assessment. Review of the U.S. Navy Environmental Health Center's Health-Hazard Assessment Process presents the subcommittee's report. The report is the work of expertise in general toxicology, inhalation toxicology, epidemiology, neurotoxicology, immunotoxicology, reproductive and developmental toxicology, pharmacology, medicine, risk assessment, and biostatistics. It is based on its review of documents provided by NEHC, presentations by NEHC personnel, and site visits to NEHC in Norfolk, Virginia and an aircraft carrier in San Diego, California.

      • Medicine
        April 2013

        Review of the Department of Labor's Site Exposure Matrix Database

        by Committee on the Review of the Department of Labor's Site Exposure Matrix (SEM) Database; Board on the Health of Select Populations; Institute of Medicine

        Beginning with the development of the atomic bomb during World War II, the United States continued to build nuclear weapons throughout the Cold War. Thousands of people mined and milled uranium, conducted research on nuclear warfare, or worked in nuclear munitions factories around the country from the 1940s through the 1980s. Such work continues today, albeit to a smaller extent. The Department of Energy (DOE) is now responsible for overseeing those sites and facilities, many of which were, and continue to be, run by government contractors. The materials used at those sites were varied and ranged from the benign to the toxic and highly radioactive. Workers at DOE facilities often did not know the identity of the materials with which they worked and often were unaware of health risks related to their use. In many instances, the work was considered top secret, and employees were cautioned not to reveal any work-related information to family or others. Workers could be exposed to both radioactive and nonradioactive toxic substances for weeks or even years. Consequently, some of the workers have developed health problems and continue to have concerns about potential health effects of their exposures to occupational hazards during their employment in the nuclear weapons industry. In response to the concerns expressed by workers and their representatives, DOL asked the Institute of Medicine (IOM) to review the SEM database and its use of a particular database, Haz-Map, as the source of its toxic substance-occupational disease links. Accordingly, this IOM consensus report reflects careful consideration of its charge by the committee, and describes the strengths and shortcomings of both. To complete its task, IOM formed an ad hoc committee of experts in occupational medicine, toxicology, epidemiology, industrial hygiene, public health, and biostatistics to conduct an 18-month study to review the scientific rigor of the SEM database. The committee held two public meetings at which it heard from DOL Division of Energy Employee Occupational Illness Compensation (DEEOIC) representatives, the DOL contractor that developed the SEM database, the developer of the Haz-Map database, DOE worker advocacy groups, and several individual workers. The committee also submitted written questions to DOL to seek clarification of specific issues and received written responses from DEEOIC. The committee's report considers both the strengths and weaknesses of the SEM and the Haz-Map databases, recognizing that the latter was developed first and for a different purpose. The committee then discusses its findings and recommends improvements that could be made in both databases with a focus on enhancing the usability of SEM for both DOL claims examiners and for former DOE workers and their representatives. Review of the Department of Labor's Site Exposure Matrix Database summarizes the committee's findings.

      • Geography & the Environment
        August 2000

        Toxicological Risks of Selected Flame-Retardant Chemicals

        by National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Board on Environmental Studies and Toxicology, Committee on Toxicology, Subcommittee on Flame-Retardant Chemicals

        Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.

      • Pollution & threats to the environment
        August 2000

        Toxicological Risks of Selected Flame-Retardant Chemicals

        by Subcommittee on Flame-Retardant Chemicals, Committee on Toxicology, Board on Environmental Studies and Toxicology, National Research Council

        Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.

      • Sustainability
        September 2020

        Biomass Production and Efficient Utilization for Energy Generation

        by N.S. Rathore & N.L.Panwar

        The book presents complicated statistical equations and formulae in the form of easily understandable text and simple formulae, so that large data gathered through the field experimentation could be properly analyzed and correct inferences may be drawn from it. The present book has been divided into seven chapters. First two chapters deals with the development of biometrics and basic statistics because biometrics cannot be understood properly without having knowledge of basic statistics. The third chapter deals with assessment of variability in a population which can be determined through different methods like D2 statistics, Euclidean cluster analysis and meteroglyph analysis, however, range, standard deviation, variance and coefficient of variation are simpler statistics for assessment of variability. Fourth chapter deals with breeding methods which include selection process, eritability, and selection index. Fifth chapter deals with aids in selection and include important topics like correlation, path analysis, regression analysis, cluster analysis, PCA and discriminant function analysis. Sixth chapter deals with aids in selection which include diallel analysis and generation mean analysis. Seventh chapter is varietal adaptation which includes stability analysis of a variety.

      • Computer networking & communications
        October 2003

        Who Goes There?

        Authentication Through the Lens of Privacy

        by Stephen T. Kent and Lynette I. Millett, Editors, Committee on Authentication Technologies and Their Privacy Implications, National Research Council

        Who Goes There?: Authentication Through the Lens of Privacy explores authentication technologies (passwords, PKI, biometrics, etc.) and their implications for the privacy of the individuals being authenticated. As authentication becomes ever more ubiquitous, understanding its interplay with privacy is vital. The report examines numerous concepts, including authentication, authorization, identification, privacy, and security. It provides a framework to guide thinking about these issues when deciding whether and how to use authentication in a particular context. The book explains how privacy is affected by system design decisions. It also describes government’s unique role in authentication and what this means for how government can use authentication with minimal invasions of privacy. In addition, Who Goes There? outlines usability and security considerations and provides a primer on privacy law and policy.

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