For all felds of the medical profession, working life has undergone serious changes: For physicians, this means providing care between the two ex­tremes – tradition and innovation. This includes topics such as digital infra­structure, electronic patient records, digital health applications, gene­based therapies, digital therapeutics, digital diagnostic methods, all the way to tele­medicine and a new type of doctor­ patient communication. In the form of structured interviews, selected ex­perts from clinics and practices as well as the healthcare industry, provide a practical insight into the digital trans­formation of the respective subsectors of medicine and an exciting outlook on future felds of action.