RANOK is the leading publishing house of Ukraine dealing with educational and children's literature. It also covers adult fiction and non-fiction/business sectors. RANOK has been working on the international market for over 20 years and has a long history of successful cooperation with many publishers around the world.
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At Penguin Random House UK, we champion the world's most brilliant voices, bringing them to life in compelling and dynamic ways for audiences everywhere. Our books shape the broader cultural life of our society and accompany people of all ages on their journey of discovery of the greatest stories, the smartest thinking and the best ideas. Penguin Random House UK Group Rights represents Foreign and Domestic Rights across the company’s seven divisions. One team represents Ebury, Cornerstone, Penguin General and Penguin Press, another represents Transworld, Michael Joseph and Vintage, and the third represents illustrated titles across the seven divisions. For more information and our catalogue, please visit our webpage.
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Vitamin D deficiency is a global health problem that puts the quality of life and life expectancy of more than a billion children and adults at risk worldwide. Many lifestyle diseases may be associated with vitamin D deficiency: myocardial infarction, infections, cancer, neurological diseases, stroke, type 2 diabetes, to name just a few. This 4th updated edition incorporates numerous new insights into the therapeutic effect of vitamin D, including its importance for a healthy pregnancy, prenatal imprinting, optimum sporting performance, diabetes mellitus and autoimmune diseases such as Hashimoto’s thyroiditis or multiple sclerosis. Since the metabolism and the effect of vitamin D are supported by a complex network of micronutrients – for example, magnesium, vitamin A or vitamin K – a specific chapter is devoted to this network. Here, the reader can discover how vitamin D successfully protects against diseases, improves the quality of life and optimises medication and treatment!
For many people, vitamin K is known only as the vitamin for blood clotting, but this is way off the mark! Science has discovered a lot of new information and nowadays it is known that in addition to its role in regulating blood clotting and the flow properties of the blood, vitamin K also promotes the health of bones and blood vessels, thus protecting against osteoporosis and arteriosclerosis. In addition, it supports a healthy glucose metabolism in diabetics and plays a role in the prevention and treatment of cancer. These are too many positive properties to leave them untapped. This patient guide informs the reader all about vitamin K
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Taking a disease-based approach, Fish Viruses and Bacteria: Pathobiology and Protection focuses on the pathobiology of and protective strategies against the most common, major microbial pathogens of economically important marine and freshwater fish. The book covers well-studied, notifiable piscine viruses and bacteria, including new and emerging diseases which can become huge threats to local fish populations in new geographical regions if transported there via infected fish or eggs. A concise but thorough reference work, this book: - Covers key viral and bacterial diseases of notable fish species; - Reviews major well-established piscine pathogens as well as new, emerging and notifiable diseases; and - Contains the most up-to-date research contributed by a team of over fifty world experts. An invaluable bench book for fish health consultants, veterinarians and all those wanting instant access to information, this book is also a useful textbook for students specializing in fish health and research scientists initiating fish disease research programmes. ; Taking a disease-based approach, this book focuses on the pathobiology of and protective strategies against the most common, major microbial pathogens of economically important marine and freshwater fish. It covers well-studied, notifiable piscine viruses and bacteria, including new and emerging diseases. ; 1: Infectious Pancreatic Necrosis Virus, Arun K. Dhar, Scott LaPatra, Andrew Orry and F.C. Thomas Allnutt 2: Infectious Haematopoietic Necrosis Virus, Jo-Ann C. Leong and Gael Kurath 3: Viral Haemorrhagic Septicaemia Virus, John S. Lumsden 4: Epizootic Haematopoietic Necrosis and European Catfish Virus, Paul Hick, Ellen Ariel and Richard Whittington 5: Oncogenic Viruses: Oncorhynchus masou Virus and Cyprinid Herpesvirus, Mamoru Yoshimizu, Hisae Kasai, Yoshihiro Sakoda, Nanako Sano and Motohiko Sano 6: Infectious Salmon Anaemia, Knut Falk and Maria Aamelfot 7: Spring Viraemia of Carp, Peter Dixon and David Stone 8: Channel Catfish Viral Disease, Larry A. Hanson and Lester H. Khoo 9: Largemouth Bass Viral Disease, Rodman G. Getchell and Geoffrey H. Groocock 10: Koi Herpesvirus Disease, Keith Way and Peter Dixon 11: Viral Encephalopathy and Retinopathy, Anna Toffan 12: Iridoviral Diseases: Red Sea Bream Iridovirus and White Sturgeon Iridovirus, Yasuhiko Kawato, Kuttichantran Subramaniam, Kazuhiro Nakajima,Thomas Waltzek and Richard Whittington 13: Alphaviruses in Salmonids, Marius Karlsen and Renate Johansen 14: Aeromonas salmonicida and A. hydrophila, Bjarnheidur K. Gudmundsdottir and Bryndis Bjornsdottir 15: Edwardsiella spp., Matt J. Griffin, Terrence E. Greenway and David J. Wise 16: Flavobacterium spp.: F. psychrophilum, F. columnare and F. branchiophilum, Thomas P. Loch and Mohamed Faisal 17: Francisella noatunensis, Esteban M. Soto and John P. Hawke 18: Mycobacterium spp., David T. Gauthier and Martha W. Rhodes 19: Photobacterium damselae, John P. Hawke 20: Piscirickettsia salmonis, Jerri Bartholomew, Kristen D. Arkush and Esteban M. Soto 21: Renibacterium salmoninarum, Diane G. Elliott 22: Streptococcus iniae and S. agalactiae, Craig A. Shoemaker, De-Hai Xu and Esteban M. Soto 23: Vibriosis: Vibrio anguillarum, V. ordalii and Aliivibrio salmonicida, Alicia E. Toranzo, Beatriz Magariños and Ruben Avendaño-Herrera 24: Weissella ceti, Timothy J. Welch, David P. Marancik and Christopher M. Good 25: Yersinia ruckeri, Michael Ormsby and Robert Davies
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Mogi Franklin is a typical eighth-grader–except for the mysterious things that keep happening in his life. And the adventures they lead to as he and his sister, Jennifer, follow Mogi's unique problem-solving skills–along with dangerous clues from history and the world around them–to unearth a treasure of unexpected secrets.In The Lady in White, Mogi is working as a cowboy over the summer vacation on one of the largest ranches in New Mexico when hundreds of cattle start mysteriously dying there. Trying to understand the cause, he finds himself embroiled in the life of a boy who was kidnapped by Comanche Indians in 1871. In this seventh book of the exciting Mogi Franklin Mysteries, Mogi comes face-to-face with the ghost of the boy's mother, and must face the reality of the past to save the ranch from the enemies of the present.
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This book is based on the real case of the original animation project "Adventure Little Prince" by several national animation companies in Hunan province. The analysis applies 3ds MAX software as the platform, includes theories and practical skills of 3D animation video creation in an all-round way from the aspects of animation plays, audiovisual language, art design, animation models, animation materials, lighting rendering, etc. All cases in the manuscript have been carefully selected and are good representations. At the same time, these project cases contain the most popular ideas and technologies, which can be well applied into practice.
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Serge Karrefax erblickt im ländlichen England kurz vor der Jahrhundertwende das Licht der Welt – und mit seinem Schicksal verwoben gleichsam das Zeitalter der Technologie und Kommunikation. Als Funker im Ersten Weltkrieg fliegt er über Frankreich, hofft im Londoner Untergrund der Swinging Twenties mithilfe technologischen Fortschritts die Toten anzufunken, und hilft schließlich im gerade unabhängig gewordenen Ägypten ein Funknetz zu errichten – bis sein Leben in einer altägyptischen Grabkammer eine unerwartete Wendung nimmt. Kommunikation, Krieg, Kokain, Krypta: K untersucht gnadenlos, unser Verlangen uns mitzuteilen, während Serge K. die Botschaft hinter allen Botschaften, das Signal hinter allen Signalen sucht. Dieses singulär originelle Buch selbst aber widersteht allen Versuchen, seinen Code zu knacken.
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This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. As well as studying the individual amino acids, including arginine, sulfur amino acids, branched-chain amino acids and aromatic amino acids, a number of themes are explored throughout the work. These include: - Comparative issues between the metabolism of microbes and those of higher organisms, including plants and mammals - Potential for drug targets in pathways of both biosynthesis and degradation of amino acids - Relationship between amino acids or associated enzymes and virulence in parasitic pathogens - Practical implications for food microbiology and pathogen characterization - Future priorities relating to fundamental biochemistry of microrganisms, food quality and safety, human and animal health, plant pathology, drug design and ecology As the volume of research into the metabolism of amino acids grows, this comprehensive study of the subject is a vital tool for researchers in the fields of biological, medical and veterinary sciences, including microbiology, biochemistry, genetics and pathology. This book is also essential for corporate organizations with active research and development programmes, such as those in the pharmaceutical industry. ; This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity - in terms of the range of organisms under investigation and their natural ecology - and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. ; -: PrefacePART I: GLUTAMATE1: Structural and Functional Properties of Glutamate Dehydrogenases2: Glutamate Decarboxylase in Bacteria3: The Yeast GABA ShuntPART II: LYSINE, ARGININE AND HYDROXYPROLINE4: Lysine Biosynthesis in Microorganisms5: Arginine Deiminase in Microorganisms6: Arginase and Microbial Pathogenesis in the Lungs7: Arginine and Methionine as Precursors of Polyamines in Trypanosomatids8: Ornithine and Lysine Decarboxylation in Bacteria9: The Role of Nitric Oxide Signalling in Yeast Stress Response and Cell Death10: Hydroxyproline Metabolism in MicroorganismsPART III: SERINE AND THREONINE11: Cellular Responses to Serine in Yeast12: Threonine Degradation in Hyperthermophilic OrganismsPART IV: SULFUR AMINO ACIDS13: Methionine Synthesis in Microbes14: Regulation of Sulfur Amino Acid Metabolism in Fungi15: Insight on O-Acetylserine Sulfhydrylase Structure, Function and Biopharmaceutical ApplicationsPART V: BRANCHED-CHAIN AMINO ACIDS16: Metabolic Engineering of Corynebacterium glutamicum for L-Valine Production17: Flavour Formation From Leucine by Lactic Acid BacteriaPART VI: AROMATIC AMINO ACIDS AND HISTIDINE18: Microbial Degradation of Phenolic Amino Acids19: The Biosynthesis of Tryptophan20: Tryptophan Biosynthesis in Bacteria: Drug Targets and Immunology21: The Kynurenine Pathway of Tryptophan Metabolism in Microorganisms22: Histidine Degradation in Bacteria23: Histidine Phosphatase Superfamily in Pathogenic BacteriaPART VII: D-AMINO ACIDS24: Functions and Metabolism of D-Amino Acids in Microorganisms25: Pathways of Utilization of D-Amino Acids in Higher OrganismsPART VIII: ECOLOGY26: Rhizobial Amino Acid Metabolism: Polyamine Biosynthesis and Functions27: Working Together: Amino Acid Biosynthesis in Endosymbiont-Harbouring Trypanosomatidae28: Amino Acid Metabolism in Helminths29: Microbial Degradation of Amino Acids in Anoxic Environments30: Utilization of N-Methylated Amino Acids by Bacteria31: Biofilm Formation: Amino Acid Biomarkers in Candida albicans32: Recent Advances Underpinning Innovative Strategies for the Future
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Von allen deutschen Autoren, die nach 1945 zu schreiben begannen, ist Artmann ohne jeden Zweifel der vielseitigste, originellste und erfinderischste. So wie Artmann in fast allen Gattungen gearbeitet hat, auch den angeblich antiquierten, und ohne sich um die Tagesparolen der mal reine Dichtung betreibenden, mal engagierten, mal die Literatur totsagenden Kollegen zu kümmern, so hat er seine Quellen, seine Herkunft überall: in der Artusepik, in barocker Schäferpoesie, in den Wörterbüchern und Grammatiken von gut zwei Dutzend Sprachen, in Irland und im England des Sherlock Holmes, bei Villon und dem Wiener Vorstadtdialekt, Lorca, Gomez de la Serna, den Surrealisten und Dadaisten, in den Detektivheftchen der 20er Jahre und den Comic strips von damals bis heute. Unsere Auswahl versucht, nicht nur einen repräsentativen Querschnitt durch das Werk Artmanns zu geben, sondern gleichzeitig Verstreutes, an entlegensten Orten Publiziertes zu sammeln.
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This definitive reference work explores the effects of current and expected climate change, taking place throughout the world, on selected bacterial, viral, fungal and parasitic infectious fish diseases of economically important fish in tropical and temperate waters.
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K u n s t / A n g s t EIN ÜBERLEBENSHANDBUCH FÜR DEN KÜNSTLER Von DAVID BAYLES & TED ORLAND Worum geht es bei Kunst? Wohin bewegt sie sich? Welche Widerstände gibt es? DAS SIND DIE FRAGEN, AUF DIE ES ANKOMMT, wiederkehrende Fragen, die sich in jedem Stadium der künstlerischen Entwicklung stellen. Sie sind der Ursprung für dieses Kompendium scharfsinniger Beobachtungen. Kunst & Angst erforscht, wie Kunst geschaffen wird, die Gründe, warum Kunstwerke oft nicht entstehen und die Art der Schwierigkeiten, die so viele Künstler dazu bringt, auf der Wegstrecke aufzugeben. Dieses Buch handelt davon, was du fühlst, wenn du in deinem Atelier oder im Lehrsaal sitzt, du an der Töpferscheibe oder am Keyboard, vor der Staffelei oder hinter deiner Kamera stehst und du versuchst, das Werk, das dir bestimmt ist, zu schaffen. Es geht darum, dass du deine Zukunft in die Hand nimmst, den Freien Willen über Vorherbestimmung, die Wahl vor den Zufall stellst. Es geht darum, dein eigenes Werk zu finden.
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The eleventh-century papal reform transformed western European Church and society and permanently altered the relations of Church and State in the west. The reform was inaugurated by Pope Leo IX (1048-54) and given a controversial change of direction by Pope Gregory VII (1073-85). This book contains the earliest biographies of both popes, presented here for the first time in English translation with detailed commentaries. The biographers of Leo IX were inspired by his universally acknowledged sanctity, whereas the biographers of Gregory VII wrote to defend his reputation against the hostility generated by his reforming methods and his conflict with King Henry IV. Also included is a translation of Book to a Friend, written by Bishop Bonizo of Sutri soon after the death of Gregory VII, as well as an extract from the violently anti-Gregorian polemic of Bishop Benzo of Alba (1085) and the short biography of Leo IX composed in the papal curia in the 1090s by Bishop Bruno of Segni. These fascinating narrative sources bear witness to the startling impact of the papal reform and of the 'Investiture Contest', the conflict of empire and papacy that was one of its consequences. An essential collection of translated texts for students of medieval history.
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Mycological paper discussing a contribution to the systematics of Cladosporium.
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Since publication of the first edition of this book, public concern for the well-being of animals has continued to increase throughout the world. In addition, advances in research over the past decade have yielded an enormous amount of knowledge about animal mental health and wellbeing. Studies on animal stress, distress, emotions, psychological trauma, and mental disorders have brought to light insights on how to care for and treat the animal mind. The second edition is:Fully revised, expanded, and comprehensively updated with the most current knowledge about the full array of mental health issues seen in animals.Written by key opinion leaders, internationally-recognized experts and specialists.Comprehensive in its coverage, from the basic principles of mental wellness, emotional distress, suffering and mental illness, through to measurement and treatment.Packed with even more practical information, wisdom and clinical tips.This book remains invaluable to veterinary professionals, animal welfare researchers and advocates, and other animal caregivers. Part 1: Foundational Issues of Animal Mental Health and Well-being 1: Mental Health in Animals: A Veterinary Behaviorist’s View — Debra F. Horwitz 2: The Problems with Well-Being Terminology — Franklin D. McMillan, James W. Yeates 3: The Philosophical and Biological Evolution of Feelings in Well-being — Ian J.H. Duncan 4: The Relationship Between Mental and Physical Health — Melissa Bain, C. A. Tony Buffington Part 2: The Pleasant Experiences: Mental Wellness 5: Moving Beyond a Problem-based Focus on Poor Animal Welfare Towards Creating Opportunities to Have Positive Welfare Experiences — David J. Mellor, Ngaio J. Beausoleil 6: The Mental Health and Well-being Benefits of Personal Control in Animals — Franklin D. McMillan 7: Quality of Life of Animals in Veterinary Medical Practice — James W. Yeates 8: The Mental Health and Well-Being Benefits of Social Contact and Social Support in Animals — Franklin D. McMillan 9: Subjective Well-being, Happiness, and Personality in Animals — Alexander Weiss, Lauren M. Robinson 10: Fostering Mental and Behavioral Wellness During Upbringing and Throughout Life — Daniel Q. Estep, Suzanne Hetts Part 3: The Unpleasant Experiences: Distress, Suffering, and Mental Illness 11: What Is Distress? A Complex Answer to a Simple Question — Franklin D. McMillan 12: Suffering, Agency, and the Bayesian Mind — Daniel M. Weary 13: Mental Illness in Animals: Diagnostic Considerations Using Selected Mental Disorders — Karen L. Overall 14: Psychological Trauma and Posttraumatic Psychopathology in Animals — Franklin D. McMillan Part 4: Mental Health Issues in Special Populations 15: Cognitive and Emotional Disorders in the Aging Pet — Jacqueline Wilhelmy, Gary Landsberg 16: Mental Health Issues in Farm Animals: A Music Mixing Board Model of Behavioral Characteristics Using The Panksepp Emotional System — Temple Grandin 17: Mental Health Issues in the Horse — Daniel S. Mills, Claire Ricci-Bonot, Sophie S. Hall 18: Mental Health Issues in Shelter Animals — Victoria Cussen, Pamela J. Reid 19: The Mental Health of Laboratory Animals — Carine Elkhoraibi, Amy Robinson-Junker, Gina Alvino, Larry Carbone 20: Mental Health Issues in Captive Birds — Lynne M. Seibert 21: Psychological Well-Being in Zoo Animals — David Shepherdson, Kathy Carlstead 22: Mental Health Issues in Captive Cetaceans — Lori Marino Part 5: Assessment and Management of Emotional Distress and Disorders 23: Assessing Affective States in Animals — Michael Mendl, Elizabeth S. Paul 24: Treatment of Emotional Distress and Disorders – Non-Pharmacologic Methods — Pamela J. Reid 25: Treatment of Emotional Distress and Disorders – Pharmacologic Methods — Sharon Crowell-Davis
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Shanka is the king's gardener. He lived in a small house with his wife. One night, unable to sleep, Shanka sat up and looked out of the window, and saw a white elephant was eating grass in the silvery moonlight! Shanka never saw a white elephant before, where was it from? Shanka jumped out of his bed and tiptoed into the garden, grabbed the elephant by the tail and flew up to heaven.
