Heart failure remains a highly prevalent and progressive syndrome with an overall prognosis as poor as that of advanced cancer. However, a wealth of promising strategies are emerging or are now available for management. We now see improved assessment, better imaging modalities, refined and individualized treatment, better pharmaco-logical and non-pharmacological interventions, dedicated follow-up and truly revolutionary device developments. At the same time, we are witnessing the beginning of the molecular revolution that will influence every aspect of heart failure care. This book of thirteen chapters from in-ternational expert authors presents a rounded overview of heart failure and its management, including etiology and pathophysiology, imaging, drug and device therapies and novel approaches.