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      • Königshausen + Neumann GmbH

        The publishing house Königshausen & Neumann was founded in 1979 by the students Johannes Königshausen and Thomas Neumann and has quickly developed into a well-known publishing house for the Humanities in a national and international context. Today we have a backlist of more than 7,000 available (!) titles, with a focus on philosophy, literature and cultural studies, history, psychology, music and art. Our aim is to accompany developments in science with publications and to make developments in science visible and accessible as such in the first place. We want to be an echo chamber not of one thought, but of a plurality of thoughts. Wittgenstein's followers, for example, are represented in our programme, as are his critics. Our authors include philosophers such as Gernot Böhme, Otto Friedrich Bollnow, Karen Gloy, Friedrich-Wilhelm von Herrmann, Vittorio Hösle and Peter Sloterdijk, and literary and linguistic scholars such as Dieter Borchmeyer, Karl Corino, Ulrich Gaier, Walter Hinderer and Volker Klotz, Wolfgang Müller-Funk, Wolfgang Riedel or Hans Rudolf Vaget, psychologists like Johannes Cremerius, Roland Kuhn or Josef Rattner, musicologists like Hermann Danuser, Frieder Reininghaus, Hans-Joachim Hinrichsen, Arnold Jacobshagen, Barbara Meier, Anno Mungen or Arne Stollberg. Many scientists have taken their first steps at K&N. Robert Habeck has published his master's and doctoral theses at K&N. Artists are represented in our programme, such as Diana Damrau, Anja Harteros or Jonas Kaufmann, Marco Goecke or Robert Tewsley. Artists are brought into conversation in a unique way: Richard Wagner or Francisco de Goya, for example. Elazar Benyoëtz entrusts us with his work, but also the young generation of writers, such as Manfred Kern, Markus Orths or Sophie Reyer, published by K&N.

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      • Neue Erde GmbH

        Neue Erde is an independent mind, body, spirit publisher with the aim to express and promote an earth-connected and life-affirming way of life through a holistic approach to nature, health and spirituality. In over 35 years of publishing history, numerous authors of Neue Erde have made a name for themselves as respected experts in their fields. We would like to offer titles that may contribute to your personal development, now and in future, because our purpose is to provide books for people who are on their path.

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      • Pollution & threats to the environment
        February 1992

        Environmental Neurotoxicology

        by Committee on Neurotoxicology and Models for Assessing Risk, Board on Environmental Studies and Toxicology, National Research Council

        Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity--the concept that long-term impairments can escape clinical detection--makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

      • The environment
        December 2006

        Assessing the Human Health Risks of Trichloroethylene

        Key Scientific Issues

        by Committee on Human Health Risks of Trichloroethylene, National Research Council

        Trichloroethylene is a chlorinated solvent widely used as a degreasing agent in industrial and manufacturing settings. It is also used as a chemical intermediate in making other chemicals and is a component of products such as typewriter correction fluid, paint removers, adhesives, and spot removers. In 2001, EPA issued a draft health risk assessment and proposed exposure standards for trichloroethylene. PA's Scientific Advisory Board (SAB) reviewed the draft and it was issued for public comment. A number of scientific issues were raised during the course of these reviews. Assessing the Human Health Risks of Trichloroethylene identifies and assesses the key scientific issues relevant to analyzing the human health risks of trichloroethylene, considering pertinent toxicologic, epidemiologic, population susceptibility, and other available information, including relevant published scientific literature, EPA's 2001 draft health risk assessment of trichloroethylene, scientific and technical comments received by EPA from public and private sources, and additional relevant information to be provided by the sponsoring agencies. This report highlights issues critical to the development of an objective, realistic, and scientifically balanced trichloroethylene health risk assessment. Guidance for hazard characterization of trichloroethylene is presented in Chapters 2 through 10. Chapter 2 provides guidance for evaluating large sets of epidemiologic data. In Chapter 3, the committee applies this guidance as an example in its evaluation of the epidemiologic data on trichloroethylene and kidney cancer, and this example should help guide evaluations of other cancer risks. Chapter 3 also assesses new information on the kidney toxicity of trichloroethylene and its metabolites and potential modes of action. Chapters 4, 5, 6, 7, and 8 evaluate the key issues regarding liver toxicity and cancer, reproductive and developmental toxicity, neurotoxicity, respiratory tract toxicity and cancer, and immunotoxicity, respectively. However, the committee's review focused on mode-of-action information to understand how trichloroethylene might affect certain processes differently in different species. Chapter 9 discusses susceptibility to trichloroethylene and its metabolites, and Chapter 10 describes important factors in considering trichloroethylene in mixtures. Physiologically based pharmacokinetic models are evaluated in Chapter 11, and guidance is provided on future directions for model development. Finally, Chapter 12 considers issues related to dose-response assessment and quantitative assessment of risk.

      • Pollution & threats to the environment
        February 1990

        Behavioral Measures of Neurotoxicity

        by Roger W. Russell, Pamela Ebert Flattau, and Andrew M. Pope, Editors; U.S. National Committee for the International Union of Psychological Science; National Research Council

        Exposure to toxic chemicals--in the workplace and at home--is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.

      • Haematology
        March 2015

        Current Approach to Hyperammonemia

        by Johannes Häberle

        Hyperammonemia is a metabolic condition characterized by increased concentrations of ammonia in the blood. Due to the neurotoxic effects of ammonia, a nitrogenous compound, it is a highly dangerous condition, particularly during infantile and early childhood development. Ammonia-induced damage to the brain may fast become irreversible depending on the duration and extent of hyperammonemia. Despite this, the mechanisms by which brain function is severely hampered or irreversibly destroyed have not yet been fully elucidated. This book brings together basic scientists and researchers, as well as clinicians caring for pediatric or adult patients, in an effort to shed light on the various biochemical, analytical and clinical aspects of hyperammonemia; it covers current approaches and the latest advances in state-of-the-art management, as well as providing future perspectives on the condition.

      • Agriculture & farming
        January 2015

        Biological Sciences

        Innovations and Dynamics

        by Rajeshwar P. Sinha, Richa & Rajesh Prasad Rastogi

        The objective of this book is to provide state-of-the-art knowledge, and highlight the current developments taking place in biological sciences. The book encompasses topics on prokaryotic cyanobacteria to higher plants, distributed in fourteen chapters for the benefit of graduate and post-graduate students as well as young researchers and scientists. Subjects covered include molecular and biochemical diversity of microbes, stress biology, cyanotoxins, antimicrobial activity of drugs originated from plants, natural bioactive compounds of microbial origin, detection approaches for genetically modified crops, genomics and proteomics. The book provides an insight for future perspectives in particular field with extensive bibliographies at the end of each . With all these, this book becomes highly useful and must-read for students, researchers and professionals in botany, biotechnology, bioinformatics, environmental sciences, agriculture, molecular biology and other streams of biological sciences.

      • Neurology & clinical neurophysiology

        Medicom Conference Reports EAN 2020

        EAN 2020

        by Prof. Hans Peter Hartung

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