Play yourself happy! The educational-therapeutic games and materials of our Sternwiese-Verlag enable individual access to the child's emotions and thoughts. With help of exciting strategies, unique concepts and personable characters will be developing and strengthening of social and emotional skills varied support.
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Discover our JUNGLE list: comic series for kids, teens and YA. Jungle recently published best-selling comic series, adapted from teens novels such as The Enola Holmes Mysteries (now on Netflix) and The Diary of an 8-bit warrior (Cube Kid). Discover our STEINKIS list: graphic documentaries and graphic adaptation for adults. Steinkis essentially publishes non-fiction graphic books (memoirs, docu-fiction, investigations) and also published graphic adaptation of literary works.
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Multi-drug resistant infections are one of the greatest threats to human health, and with resistance on the rise, appropriate antimicrobial stewardship (AMS) is more important than ever. This book, written by nurses for nurses, provides a clear and concise approach to good practice in this vital area. It explores all aspects of AMS, explaining the practices that ensure the optimal use of antibiotics for the best clinical outcome, with both minimal toxicity to the patient and minimal impact on subsequent antimicrobial resistance. Written by a global team of experts, it covers infection prevention and control, antimicrobial resistance, diagnosis of infection and appropriate antimicrobial use, patient engagement, collaboration between professions and how to implement AMS in nursing practice. The first AMS textbook applied directly to nursing practice, and underpinned by a competency framework designed by the editor team, it includes learning tools such as objectives, practical case studies and questions throughout.
In an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration. ; Antimicrobial research has hit a wall: treatment discoveries are rarer and resistant pathogen strains more prevalent. Rather than infection control itself, antimicrobial stewardship is an essential measure in ensuring management of hospital-acquired infections. Throughout this book, international experts discuss all angles of stewardship. ; Part I: Overview of Antibiotic StewardshipCh.1: Principles of Antimicrobial StewardshipCh 2: Clinical Perspective of Antimicrobial StewardshipCh 3: History of Antimicrobial StewardshipCh 4: The Importance of Education in Antimicrobial StewardshipPart II: Antibiotic Resistance Principles in Antibiotic Stewardship Ch 5: Intrinsic and Acquired Mechanisms of ResistanceCh 6: Antimicrobial Resistance: Selection vs. InductionCh 7: Colonization and its importance for emergence of clinical resistanceCh 8: Antibiotic Resistance: associations and implications for antibiotic usage strategies to control multi-resistant bacteriaPart III: Microbiology Laboratory Role in Antibiotic StewardshipCh 9: The role of active surveillance in the prevention of healthcare-acquired infections and antibiotic stewardshipCh 10: Role of Antibiogram in Antibiotic StewardshipCh 11: Selective Reporting and Antimicrobial StewardshipCh 12: Role of New Diagnostics to Enhance Antibiotic Stewardship EffortsPart IV: Infection Control Aspects of Antibiotic StewardshipCh 13: Epidemiology of S aureus and enterococci in children and an overview of antimicrobial resistanceCh 14: Epidemiology of multi-drug resistant gram-negative organismsCh 15: Pathogenesis and Epidemiology of Clostridium difficile Infection: Implications for Antibiotic StewardshipCh 16: Role of the Hospital Epidemiologist in Supporting Antimicrobial StewardshipPart V: Pharmacokinetic (PK) & Pharmacodynamic (PD) Aspects of Antibiotic Dosing in Antibiotic StewardshipCh 17: Principles of Pharmacokinetic / Pharmacodynamic Optimization for Antibiotic DosingCh 18: Optimal use of Gram-negative antibiotics in the real world: providing effective therapy while minimizing resistanceCh19: Optimal Use of FluoroquinolonesCh 20: Optimal Use of Beta-lactam AntibioticsCh 21: Current Approach to Optimal Use and Dosing of Vancomycin in Adult PatientsCh 22: Principles of IV to PO SwitchPart VI: Pharmacy Department Role in Antibiotic StewardshipCh 23: Role of Pharmacists in Antimicrobial StewardshipCh 24: Formulary Management and Economic Considerations; Bridging the Gap between Quality Care and CostCh 25: Approaches in benchmarkingCh 26: Development and execution of stewardship interventionsCh 27: Technologic support for antimicrobial stewardshipPart VII: Measuring Outcomes in Antibiotic Stewardship ProgramsCh 28: Role of Guidelines and Statistical Milestones for Antimicrobial StewardshipCh 29: Economic considerations of Antimicrobial Stewardship ProgramsCh 30: Pharmacoeconomic Implications of Antimicrobial Adverse EventsCh 31: Antimicrobial stewardship programs in areas of increased pathogen resistancePart VIII: Antimicrobial Stewardship and Various Practice SitesCh 32: Role of Antimicrobial Stewardship in PediatricsCh 33: Antimicrobial Stewardship in the Intensive Care UnitCh 34: Role of Antimicrobial Stewardship in a Community HospitalCh 35: Outpatient Parenteral Antimicrobial Therapy (OPAT)Ch 36: The Importance of Interdisciplinary Collaboration in Antimicrobial Stewardship: Immersion of Future Healthcare ProfessionalsCh 37: Antimicrobial Stewardship and the Importance of Working with the Government and Pharmaceutical IndustryCh 38: Hospitalist Perspective on the Role of Antimicrobial Stewardship
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Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs. Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents. Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel.
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Antimicrobial Peptides (AMPs) are an organism's built-in defence molecules that have attracted extensive research attention worldwide. Harnessing and creating them synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. In addition to covering the current advances in AMP research, this volume examines new technologies such as bioinformatics, combinatorial libraries, high-throughput screening, peptidomimetics, biophysics, and structural biology. This volume also describes new methods and strategies for AMP prediction, design, and applications that overcome obstacles in developing them into therapeutic agents.
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Globally, the way the animal production industry copes with infectious diseases is changing. The (excessive) use of antimicrobials is under debate and it is becoming standard practice to implement thorough biosecurity plans on farms to prevent the entry and spread of pathogenic micro-organisms. Not only in farm animal production, but also in facilities where companion animals are kept, including in veterinary practices and clinics, awareness of the beneficial implications of a good biosecurity plan has raised. The book Biosecurity in Animal Production and Veterinary Medicine is the first compilation of both fundamental aspects of biosecurity practices, and specific and practical information on the application of the biosecurity measures in different animal production and animal housing settings. The book starts with a general introductory chapter on the epidemiology of infectious diseases, followed by a chapter explaining the general principles of biosecurity. Specific topics of biosecurity, including rodent and insect control, cleaning and disinfection, hygiene and decontamination of feed, drinking water and air, and measuring the biosecurity status of farms, are detailed in dedicated chapters. Explanations on the relevance of the implementation of biosecurity plans in order to improve animal health and performance and reduce antimicrobial usage are described, and a chapter on ways to motivate farmers to implement a biosecurity plan has been included. Practical chapters deal with biosecurity in the poultry, pig and cattle industry, horse facilities, dog kennels, veterinary practices and clinics and laboratory animal facilities. The book is a practical guide that can be used by farm and animal facility managers, consultants, veterinarians, animal caretakers, and people with an interest in prevention of diseases in animals. Academics and students will benefit from the book because it contains all relevant information on animal biosecurity.
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Drug resistance is increasing among a variety of human pathogenic microorganisms such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumaniii, Pseudomonas aeruginosa and Enterobacter spp. (currently dubbed the 'ESKAPE' pathogens), and has emerged as one of the most important clinical challenges of this century. Increased general awareness and fear of these pathogens means there is a growing demand for research to tackle the threat of multidrug resistance. Documenting the latest research in the field, this book discusses current and promising activities to discover new antimicrobials in five key areas: molecular genetics and systems microbiology; synthetic, computational chemistry and chemoinformatics; High Throughput Screening (HTS); non-vertebrate model hosts; and light- and nano-based technologies.
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The demands of producing high quality, pathogen-free food rely increasingly on natural sources of antimicrobials to inhibit food spoilage organisms, foodborne pathogens and toxins. Discovery and development of new antimicrobials from natural sources for a wide range of applications requires that knowledge of traditional sources for food antimicrobials is combined with the latest technologies in identification, characterization and application. This book explores some novel, natural sources of antimicrobials as well as the latest developments in using well-known antimicrobials in food. Covering antimicrobials derived from microbial sources (bacteriophages, bacteria, algae, fungi), animal-derived products (milk proteins, chitosan, reduction of biogenic amines), plants and plant-products (essential oils, phytochemicals, bioactive compounds), this book includes the development and use of natural antimicrobials for processed and fresh food products. New and emerging technologies concerning antimicrobials are also discussed.
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Provides consumer health information about food safety, antimicrobial use, common foodborne pathogens and illnesses, basic food safety in the kitchen, safety by events and seasons, allergies, and intolerance. Includes index, glossary of related terms, and other resources.
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Plants produce secondary metabolites with herbicidal, insecticidal, fungicidal and antioxidant activities. This book provides an up-to-date treatment of antioxidant and biocidal compounds mainly from Latin American plants. New antimicrobials, insecticidals, and antioxidants are covered in three sections: a general overview and perspectives on antioxidant, medicinal and biocidal plant compounds; details of plant antioxidants isolated from a wide range of species; insecticidal, antimicrobial and other biocidal activities based on peptides, phytoecdysteroids, alkaloids, polyphenols, terpenoids and other allelochemicals.
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Overzealous and indiscriminate use of many synthetic pesticides during recent decades in the control of plant pests has resulted in a number of environmental and toxicological problems. Reducing the release of synthetic chemicals into the environment requires that alternative sources of chemicals are developed that can be used safely in the management of plant pests. Botanical antimicrobials derived from plants are currently recognised as biodegradable, systemic, eco-friendly and non-toxic to mammals and are thus considered safe. Their modes of action against pests are diverse. Natural compounds are well suited to organic food production in industrialised countries and can play greater roles in the protection of food crops in developing countries Some plant based antimicrobials (e.g. neem products, pyrethoids and essential oils) are already used to manage pest populations on a large scale. Plant scientists and agriculturists now devote significant attention to discovery and further development and formulation of novel plant products with antimicrobial activity.This book is the first to bring together relevant aspects of the basic and applied sciences of natural pesticides and discussed modern trends in the use of natural products in pest management.
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Poultry are a major source of valuable high-quality protein for much of the world's population, so food security is heavily dependent on maintaining poultry health. They are also increasingly important as specialist hobby animals in back-yard flocks. Despite this, veterinarians specializing in the care and health of these important domestic animals are few and far between, and many vets in small animal practice have little real experience of poultry health management and disease. Providing a comprehensive overview, this new handbook will help to plug this gap with 46 chapters of practical and accessible poultry health and management. The book: Covers the poultry industry, basic avian biology, infectious and non-infectious diseases and their agents, infection control, and disease investigation and legislation. Includes full colour images for ease of identification and diagnosis, in addition to practical guides to disease prevention. Considers areas of increasing global importance, such as antimicrobial resistance. Written by international experts, this book forms a valuable illustrated resource for veterinary professionals, veterinary students, or those entering the poultry industry.
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During the last decade, there has been a shift in the governance and management of fisheries to a broader approach that recognizes the participation of fishers, local stewardship, and shared decision-making. Through this process, fishers are empowered to become active members of the management team, balancing rights and responsibilities, and working in partnership with government. This approach is called co-management. This handbook describes the process of community-based co-management from its beginning, through implementation, to turnover to the community. It provides ideas, methods, techniques, activities, checklists, examples, questions and indicators for the planning and implementing of a process of community-based co-management. It focuses on small-scale fisheries (freshwater, floodplain, estuarine, or marine) in developing countries, but is also relevant to small-scale fisheries in developed countries and to the management of other coastal resources (such as coral reefs, mangroves, sea grass, and wetlands). This handbook will be of significant interest to resource managers, practitioners, academics and students of small-scale fisheries.
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Invasive species are among the greatest challenges to environmental sustainability and agricultural productivity in the world. One of the most promising approaches to managing invasive species is voluntary citizen stewardship. However, in order for control measures to be effective, private citizens often need to make sustained and sometimes burdensome commitments. Community-Based Control of Invasive Species is based on five years of research by leading scholars in natural resource and human behavioural sciences, which involved government and citizen groups in Australia and the United States. It examines questions including, 'how can citizens be engaged in voluntarily managing invasive species?', 'what communication strategies will ensure good motivation and coordination?' and 'how can governing bodies support citizens in their efforts?'. With chapters on institutional frameworks, changing governance, systems thinking, organisational learning, engagement, communication and behavioural change, this book will be a valuable reference for researchers and practitioners involved in natural resources management.
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Around the world, there is mounting evidence that parks and protected areas contribute to a healthy civil society, thus increasing the economic importance of cultural and nature-based tourism. Operating at the intersection of business and the environment, tourism can improve human health and wellbeing as well as serve as a catalyst for increasing appreciation and stewardship of the natural world. While the revenues from nature-based activities help to make the case for investing in park and protected area management; the impacts they have need to be carefully managed, so that visitors do not destroy the natural wonders that attracted them to a destination in the first place. This book features contributions from tourism and recreation researchers and practitioners exploring the relationship between tourism, hospitality, protected areas, livelihoods and both physical and emotional human wellbeing. The book includes sections focused on theory, policy and practice, and case studies, to inform and guide industry decisions to address real-world problems and proactively plan for a sustainable and healthy future. Key features: Case studies discussing best practices for park and protected area tourism development Multi-disciplinary approach to the study of nature-based tourism Innovative approaches including SME within protected destinations
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Robust health care systems are paramount for the health, security, and prosperity of people and countries as a whole. This book provides for the first time a chronicle of the struggle for, and eventual success of, universal health coverage (UHC) in Tanzania. Beginning with an introduction to primary health care in the country, from its historical foundations to the major milestones of implementation, this book then considers stewardship of this important aspect of health systems over time. Written in a way to allow the application of lessons learned to other countries' contexts, this book covers: - Policy and governance issues such as leadership, human resources, and financing of health systems; - Practical aspects of health system delivery, including supply chains, community care, new technologies, and the integration of services for particular population groups; - The impact and mitigation of global events on health systems, such as resilience and preparedness in the light of disease outbreaks or climate change, and social, commercial, and political influences. Concluding with a look to the future, forecasting the changes and new solutions needed to adapt to a changing world, this book is a valuable reference for policy makers, global health practitioners, health system managers, researchers, students, and all those with an interest in primary health care and reforms - both in Tanzania and beyond.
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Poultry are the most widely used animal protein source in the world: billions of meat birds are produced globally each year, using 360 million tonnes of feed. Within Europe, over 30,000 companies involved in the production of poultry create an annual turnover of €107 billion. However, maintaining the sustainability of the industry as it moves towards antibiotic-free production is one of the key challenges. Starting with an overview of antibiotics as growth promoters and the challenges faced as the industry moves away from their use, this book then thoroughly considers the potential of pre and probiotic additives in poultry gut health. The book: - Includes thorough definitions of additives in the pre and probiotic space and examples of how they work; - Addresses how to test pre and probiotics and other similar additives, and how they interact with other products, with learning from both poultry and allied sectors; - Combines authors from both academic and industry backgrounds on all chapters, to ensure coverage is balanced, robust and commercially relevant. Based on the renowned World Poultry Science Association UK Branch Poultry Science Symposium 2022, this book provides a thorough and valuable contribution to the field for all involved with the nutrition and production of poultry.
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wine can be infected with many different mycoplasmas. Some are important pathogens, causing significant health and welfare issues in pigs and major losses to the swine industry worldwide. Other mycoplasmas are not pathogenic for swine and can be considered commensals. This book provides up-to-date scientific, clinical and practical information of the most important pathogenic mycoplasmas in swine. Most emphasis has been placed on Mycoplasma hyopneumoniae as the most economically important, but other pathogenic species like Mycoplasma hyorhinis, Mycoplasma hyosynoviae and Mycoplasma suis are also discussed.Written by internationally renowned scientists and clinicians from all over the world, this book draws together in depth knowledge, expertise and experience in swine mycoplasmas to provide an evidence-based, academically rigorous and practical collection. It aims to serve the scientific and veterinary community and the swine industry worldwide. 1: Overview of the general characteristics and classification of porcine Mycoplasma species 2: Diversity of Mycoplasma hyopneumoniae strains 3: Mycoplasma hyopneumoniae pathogenicity: the known and the unknown 4: Epidemiology of Mycoplasma hyopneumoniae infections 5: Mycoplasma hyopneumoniae clinical signs and gross lung lesions, including monitoring 6: Immune responses against porcine Mycoplasma infections 7: Interactions of Mycoplasma hyopneumoniae with other pathogens and economic impact 8: Diagnosis of Mycoplasma hyopneumoniae infection and associated diseases 9: General control measures against Mycoplasma hyopneumoniae infections 10: Antimicrobial treatment of Mycoplasma hyopneumoniae infections 11: Vaccines and vaccination against Mycoplasma hyopneumoniae 12: Eradication of Mycoplasma hyopneumoniae from pig herds 13: Mycoplasma hyorhinis and Mycoplasma hyosynoviae in pig herds 14: Mycoplasma suis infections in pigs
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Although at first Covid-19 disease was only evident in China, during the months of January to March 2020, it spread across the whole world with far-reaching consequences. This guide contains ■ The background to the character of the virus and its spread ■ Various information about the consequences for the operation of a pharmacy, including an emergency plan ■ Precise instructions for the in-house production of disinfectants. The guide also tackles questions and problems relating to employment law that arise in connection with the risk of infection in public premises.
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More than two years of pandemic is more than two years of corona clutter. Only a staggering level of helpfulness, improvisation and flexibility prevented the healthcare system from collapsing completely. In this highly topical book, pharmacist Simon Krivec tells of his incredible experiences and the stormy ups and downs of pandemic madness, missing masks and disinfectants, and the feeling of having been totally abandoned by a helpless state. We learn, for instance, of the short-term procurement of large quantities of ethanol and the transportation of the highly flammable substance, and just what lured the author – and 71,400 euros in cash – to visit the port of Neuss at night.
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The construction, control and preservation of the Official Record is inherently contested. Those seeking greater openness and (democratic) accountability argue 'sunlight is [...] the best of disinfectants', while others seek stricter information control because, to their mind, sound government arises when advice and policy are formulated secretly. This edited volume explores the intersection of the Official Record, oversight, national security and democracy. Through US, UK and Canadian case studies, this volume will benefit higher level undergraduate readers and above to explore the Official Record in the context of the national security operations of democratic states. All chapters are research-based pieces of original writing that feature a document appendix containing primary documents (often excerpts) that are key to a chapter's narrative. As a result, this book interrogates the boundaries between national security, accountability, oversight, and the Official Record.
