Tissue analysis plays an important role in drug discovery and development. The purpose of tissue analysis varies depending on the type and stage of the drug discovery and development, and there is no one-size-fit-all solution. In the six chapters of this book, the authors highlight the critical aspects and considerations of tissue analysis. They summarize the general principles and processes in tissue analysis with useful and practical information so that the reader is then able to identify the critical factors and address their own particular challenges. This timely compilation describes the typical methodologies and current practices of tissue analysis in drug development, together with some case studies. It is intended for researchers who have a general knowledge of bioanalysis but may or may not have extensive exposure of tissue analysis, and is also relevant to researchers in other fields, such as environmental monitoring and food testing.