Hypertension remains the number-one risk factor for cardiovascular disease and mortality, in spite of significant progress in understanding of the mechanisms that control blood pressure, of the pathogenesis of hypertension, its genetics, new antihypertensive agents, and community and population efforts to control blood pressure. In this volume of 17 chapters, the Editors have assembled a group of leading investigators in basic, clinical, epidemiological and population science of hypertension. Each has provided an evidence-based, albeit personal, view of salient aspects of blood pressure regulation, mechanisms, diagnosis and treatment, all within a limited number of pages to make this useful and easy to ‘digest’, but at the same time, a learned source of the latest science in the field. The book explains recent developments in the field and provides practical knowledge for those involved in research, teaching and care delivery to patients with high blood pressure.