Psychiatric illnesses with onset during adolescence and early adulthood recur or persist lifelong, and are associated early in their course with suicide, addictions and an elevated risk of chronic medical disorders. Furthermore, the average time to accurate diagnosis is estimated at 8–10 years after the onset of full-threshold illness. Improving accurate, early detection and developing effective prevention and early intervention strategies are therefore of paramount importance, and this book of ten chapters provides updates on the key aspects of these goals in bipolar disease from leaders in this field. The book is a key resource toward improving outcomes for bipolar patients and their family members.